{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022mEzqf8GkvNWYbl0Z1s1w31wkz71wjUwp6qKpRdFBHioKZ7pIl31RVXRn5YHcmrTxghHTO0F+F0YvYlYn5FzgwkeR8MwR2z3t1+sN7l34t4g8+IVPtvs36uSVmkJLjYeE4J50+jhr32V6cNfPNKqVEzP7Ms83Rl+oxWXviD20Se+CLbh6QHL64j6634wgYtMlZaok2D1+Mlt0hZfWRS+PNzC0lFIeV18ZV0GPBlY\\\\\\\\\\\\\\\/WUQuGdHlpTu0yOSxJvOz\\\\\\\\\\\\\\\/lAqe4sJXA5RCZfCUNpA8JDLzaD2MEIfZhUc10fH5ksXgsm39jPMxwk4hJLWY3KWjxhxBsdQjxHtNDacBc+k+B1FP+iKEaIZcQIwxwSYvIgm8WJkAwWPwCYeWDMMltv468WpQzUqVJWkC3jOJ0POj3xLRwM0+eHd+wSlJcRc6UX6GpOIRjTdq0x0P3CcuTtc+uGGuWK5J1aPHbzAfj9D9qfFp0bE9J0R9yf7e6H+sxoEpTBMl6cSamOUgYoDWo5VdNTD\\\\\\\\\\\\\\\/Rrulq9x9u7cIoWb7FsBKiDKbHRD0ZZVmSK2XUej\\\\\\\\\\\\\\\/Lnc9i+oANWTnRiXpTZB4JC+nLJAxbGiqgp5l\\\\\\\\\\\\\\\/TYx6Cguuh8RexnNdh6R8xWwNnJc6C8aLzxVu5M3auTGJVUa81AjXqU+c0bPD0VLZLWlkMtVDsBdFR5kVGGDMufRgad2HmsKORpf1fxp4r0MHNwvZL6GRCPNhUXURQRGwI4em8UTzUW5V3Xt4\\\\\\\\\\\\\\\/rPoOsq3NAygQV7IAxntldOY5uNKgXMJwhy+SWT3PXp2IC7EdbFGNWDJ5rTpZdZk\\\\\\\\\\\\\\\/k2w2vIWwzeFMDdA1ZOrcGKIXK2bU1T5LI9OJIL\\\\\\\\\\\\\\\/mqAZyKRRtORyQEOdM4FeY9prltGWaHwqrVr9kDlpDreRcHFthWpXxvFOp1nNQ8jifhGDB\\\\\\\\\\\\\\\/qW6xpEBK1LYhBIuTQag5Z1sEE3WtImJ+Mr6gdTZkC3Fy04hbq\\\\\\\\\\\\\\\/Xv4HAOV6mRmhLJa1y2OjjMIbDpOWOrvx4qSn89wz7AoceCVQ5hMvwHuIQbKYdoZHX+PzPJpAjYr3bV4+iR8DRoojhp0FaRMgl4QnhGk8sl5DFS+ahsoR4Dk7l8AT+S6HxMhf7KUXPGYt8x9lZ6HMG2QCsFuXtmnrUB0wXaYPf2nFVhWPP6TK7ZJq8\\\\\\\\\\\\\\\/wq\\\\\\\\\\\\\\\/yqd+b9PyA27YfnMaxIcvXWZL5jaoRldyqrw8vIqXPkNhyl3OD2N0fqVrwYt+pRDSwae4ZJAkDXOqGzdhjcxJmL8\\\\\\\\\\\\\\\/MXOU4fe8d\\\\\\\\\\\\\\\/21tucJRFMKA7RsmQZcVUFOidv99ERZ+6wGt+GAMHKpTY3JHm+k53pDGSi6q+ZBVtpg\\\\\\\\\\\\\\\/bLmY8Xd2PHJW\\\\\\\\\\\\\\\/be82DXNDrF4bvlISuKSykjzWPVM1FZR2puCGmQd7RbLelZczhJmVnKMaG6EdUt0SZ0QSe+P7yyONyScHizhB\\\\\\\\\\\\\\\/SocelM4\\\\\\\\\\\\\\\/wHwgmMyzqe\\\\\\\\\\\\\\\/QUfvYvsyFxVAC9L1FGvGaJCfab\\\\\\\\\\\\\\\/3KxSBpUCoXfUlqkEkCduVFCCBB7B6mYLXGBHxXeFLJyU1pMl36bBWgZV4VrboBxyNcpc+46DDS+QUzD5a2LXceKjwO2gZyi+y7NJ9O8IIzsVIiApqQDXBSYay\\\\\\\\\\\\\\\/f0TA8YUCBeVVjojWgCWkU2MV9Vy0CmgRmBfLmRZJEVxLtlx2nu89c1Fm1WdLYv5Eblaf6BWCrAHxmtM5fgeLcSMMj\\\\\\\\\\\\\\\/zaQ3PWgcrlfKYZAmuxXfDSWelWziyfaAG9jlgEW0lkCyy0Y3SnJFcK0r3XAL74OnOv6dOmL1O0AHKBTL\\\\\\\\\\\\\\\/Uvk3pB6byAGDlAwkenvzO3SppH0XTCvq9l58qpfzLNy6TcUfYOWGStSITdsA4\\\\\\\\\\\\\\\/b15fqKtFHDcC5hYrRJYW2MObHCS\\\\\\\\\\\\\\\/\\\\\\\\\\\\\\\/8x+MhnVXeFKiyBjxDHcxBx5e8s\\\\\\\\\\\\\\\/dm1A0o2hpWr1ArNI6qCPHphqtl43iAp6ZJ3C2sXaUXBxMoJ5Ulo1jD7OLu0jzuz8lhlZWO1pgKulJ4js6MRKmLkifArCZzMkwTqPUzg\\\\\\\\\\\\\\\/BxFh98Q43o3zeEAZ\\\\\\\\\\\\\\\/ckDYCcalz1AJ1Y6YxnJEWjtElv9Y6W0T0uk2oK8nCCP8bawoxE72iJuVRxXjNn7EZqI\\\\\\\\\\\\\\\/\\\\\\\\\\\\\\\/a6QylpAY7C8TDFqLWT+OCziSHWu2DDmKSDaW+qbmMy4GdRIinmESZtlKScEBBjCfrgV9p\\\\\\\\\\\\\\\/\\\\\\\\\\\\\\\/Zvu2EGu6F2oviGPGGbHnXLKzwNkhTBemfr\\\\\\\\\\\\\\\/Z3aNekT9OaIwPnmPnMdGDZ2neaZyuUeZc\\\\\\\\\\\\\\\/pqRHBeAUtpLaBQodLMg44pIlHvPdrK3BDwUg5RWdYGnVX9aMQQ1eYKOIrnqSql2lLNGeetEpHjvoAwyIXfEVTnGVMj38zuLTnScqqPy58NliCVsbfy1xJVywUf0\\\\\\\\\\\\\\\/d0kYiy8d0vKrp1\\\\\\\\\\\\\\\/zHBtEDD2t+11EBo27N1oM01NiY3rDTENOeFpztAmqFKBrHBIfAx+tuh5s0oJRMPMDqtjoVQ75otRUZ1D5NoM81FSiH0aOk+eKQk6N0EvsdQuP2vnlVt+41b0y0szrOStku0vxjjg10dBmLroLQyqYEp36KhsEtf+WbxRmJEAD8veL3EY8tJGvyyqq50YoKt65es3Y\\\\\\\\\\\\\\\/NnEjL9n2UoX4HU3pC0FSBpGIr94HSJF8x9q+tmVKr0\\\\\\\\\\\\\\\/lD9apdvQIqIJkTfQY8PFwDf6wQ=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022fjAcnNYQ93eHLpeHNbCJtA==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u00223abf5f8c323f97ec4ec15541e15bb78d765f8ff1b2f614ec08cb2979ca1a94cd\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/8\\\/1\\\/e000208.atom\u0022:{\u0022access\u0022:{\u0022full\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/8\\\/1\\\/e000208.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2019-000208\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2019-000208\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2019-000208\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}