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data-content-type=\u0022city\u0022\u003ERockville\u003C\/span\u003E\n\u003Cspan class=\u0022nlm-addr-line\u0022 data-content-type=\u0022state\u0022\u003EMD\u003C\/span\u003E\n\u003Cspan class=\u0022nlm-country\u0022 data-country=\u0022US\u0022\u003EUSA\u003C\/span\u003E\n\u003C\/span\u003E \u003Ca href=\u0022\/lookup\/external-ref?access_num=Wigginton%20JM\u0026amp;link_type=AUTHORSEARCH\u0022 target=\u0022_blank\u0022 class=\u0022authour-link\u0022 data-icon-position=\u0022\u0022 data-hide-link-title=\u00220\u0022\u003EPubMed articles\u003C\/a\u003E\u003Ca href=\u0022\/lookup\/google-scholar?author%5B0%5D=%22author%3AJon%20M.%20Wigginton%22\u0026amp;gs_type=author\u0022 target=\u0022_blank\u0022 class=\u0022authour-link\u0022 data-icon-position=\u0022\u0022 data-hide-link-title=\u00220\u0022\u003EGoogle scholar articles\u003C\/a\u003E\u003C\/li\u003E\u003Cli class=\u0022last even\u0022\u003E\u003Cspan class=\u0022nlm-given-names\u0022\u003EPeter P.\u003C\/span\u003E \u003Cspan 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pane-highwire-article-citation\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ECitation\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022highwire-article-citation highwire-citation-type-highwire-article node5443\u0022 data-node-nid=\u00225443\u0022 id=\u0022node-5443--21370207053\u0022 data-pisa=\u0022jitc;5\/1\/38\u0022 data-pisa-master=\u0022jitc;10.1186\/s40425-017-0241-6\u0022 data-apath=\u0022\/jitc\/5\/1\/38.atom\u0022\u003E\u003Cdiv class=\u0022highwire-cite highwire-cite-highwire-article highwire-citation-v1-cp clearfix bmjj-article-citation\u0022\u003E\n  \n  \n    \t\u003Cdiv class=\u0022highwire-cite-authors\u0022\u003E\u003Cspan class=\u0022highwire-citation-authors\u0022\u003E\u003Cspan class=\u0022highwire-citation-author first\u0022 data-delta=\u00220\u0022\u003E\u003Cspan class=\u0022nlm-surname\u0022\u003EKaufman\u003C\/span\u003E HL\u003C\/span\u003E, \u003Cspan 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highwire-cite-metadata\u0022\u003E2017;\u003C\/span\u003E\u003Cspan class=\u0022highwire-cite-metadata-volume highwire-cite-metadata\u0022\u003E5:\u003C\/span\u003E\u003Cspan class=\u0022highwire-cite-metadata-elocation-id highwire-cite-metadata\u0022\u003E38. \u003C\/span\u003E\u003Cspan class=\u0022highwire-cite-metadata-doi highwire-cite-metadata\u0022\u003E\u003Cspan class=\u0022label\u0022\u003Edoi:\u003C\/span\u003E 10.1186\/s40425-017-0241-6 \u003C\/span\u003E\u003C\/div\u003E\n  \n  \n  \n\u003C\/div\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-mini pane-jnl-template-bmjj-art-pub-history\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panel-display highwire-1col-stacked-layout\u0022 id=\u0022mini-panel-jnl_template_bmjj_art_pub_history\u0022\u003E\n\t  \n  \u003Cdiv 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