{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_M8BsRY25PLDHBensqRcUs1nEubvHeoGn5HSxBrIWeZs.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-d5e9ecaa-460b-40c1-87fb-0dbcbc3a749d\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u00228IqRtfoCoLljVCExXoGClN7gIineVgQ7QVYFKO6ZUgqen\\\\\\\\\\\\\\\/mCFVZ+u2NGggJoCKv\\\\\\\\\\\\\\\/kCxqrVWjaaQjaodBRw6YDQX9W4BuDBzYVmiaxmMH4Yf\\\\\\\\\\\\\\\/zVg7\\\\\\\\\\\\\\\/e\\\\\\\\\\\\\\\/3AbU6bi61fP4V4qhUKPylZux6\\\\\\\\\\\\\\\/cl1Xgui2HPRbpNz4Efi94agZ2P6NrabxPK98af08NUA0S6m+0t5\\\\\\\\\\\\\\\/5sdxu3fSWzDy+9UoQt0vKFs1pu\\\\\\\\\\\\\\\/7M0p2neqSMVPYx0HEcKfrT2FZ2D8QzrpuAkb6diQ3jLxjieBQG5pClzfbAUEyPX1WC9SBgAlyUoWvuG5NIBn6zdzm5WwzP1rVkMjElVVvVstMzaWmchfNNC0Y49L2+qAADf3Tjs1G9\\\\\\\\\\\\\\\/5jX\\\\\\\\\\\\\\\/tpFzW5Rm8SjKJZ65keqpj4zXzoV\\\\\\\\\\\\\\\/Am57hYcwmNbY2T1shhMNzY4IcLcc5m\\\\\\\\\\\\\\\/rwVQzXRiBwDJPCf7T7pyoeeC70iwJib+gWFGj4rDPFe3cepVZAMSHu1yIrARecOxyUHke9CTzFAL+FAWDVy1zfgcP1WO7BJovig68nT7NuYiKQBJSLSTMiahflhkcVmtvd4QYHMD4I07WOoyKnkl9sd\\\\\\\\\\\\\\\/Y8CL\\\\\\\\\\\\\\\/q1NaQvjEotURRt\\\\\\\\\\\\\\\/UV0AbVfOCU2g8H5GLHGubxwoR6fSkx5ZwkUl4Ixfxvkjf4L5ohq3DmvKYRaNyeqceaR+rkyRyQFZlo1jC43gWYDN8E4rw0AifQPH7L6PORwCmEcz2NZrK5wZCNr6Z0E\\\\\\\\\\\\\\\/LF+KKiJlyL0VDHH3fX0HEvUn8gp7PEf1zeMNVo4gRT\\\\\\\\\\\\\\\/sI0T78Qad4vmj\\\\\\\\\\\\\\\/34UynhTVbaO5Nx3XUVW6cFM4spFY05Fkzo5DNMVh6iCm6vqFFcrNh1wCTl90qh2orUX\\\\\\\\\\\\\\\/VGDVPh4bxi8E+PcfxZ3FttrRzgshq+FiStV0HpH2H1emH\\\\\\\\\\\\\\\/6NrE9SAEmG13hmtx5dLqd3zK7hokt9Jf2AH87Y9uXKsMNISZD5cL6mgbb\\\\\\\\\\\\\\\/kRDXlaJBWFLwpE\\\\\\\\\\\\\\\/4vfYMova6yieTMR2t1xJlfkk+KJ5J52fZBLXaDhP3c1QDiJdzhTykxM5LRMFV4zuSDIEL1vh1cylh9D15zzQjP24pIai0qmIA9UYd5sobTPGyCQIvsLoNTGBwCMPvI5lO398N6jVPye7D8UC0ZFtRhLxs4ozc8oCwPGXKdKiKli2iRJeuuX7vfLO9s\\\\\\\\\\\\\\\/5faBJQZYwtjptQXvVzMbYl71RPBowWVPdV0ekcYpWtqw\\\\\\\\\\\\\\\/N5fkhp0GPhXPxRs57iPNk49fJnJGZXebGf6hhCNwWdh7xm0UovBUEe1dNXzUE7txJ6M6VWdNZuwg7fh0tkTkEFhoXFsJl5hT+70JUyaCmRUgXGKmHnIDM7pfTDQ9s1Yn5XPcIG9wxFO3pvrbARw5bmws8SnxZHJi97E342wFS4Xdkru4Qt5jCWcVisAup8jBxiX3qSHbortA80dzLhacEh+kq3A6PCYLck3VxokTFYFg8gkuLo6\\\\\\\\\\\\\\\/zoSiEoLR4loTpQfvDDaMNilG+\\\\\\\\\\\\\\\/HnaF5CWuCR\\\\\\\\\\\\\\\/K+BnjMOyo8rEx71HrdmcrPnr7u+nURrKiwpCy5Ss\\\\\\\\\\\\\\\/FRCGdFjyRFLqy82fTsN\\\\\\\\\\\\\\\/QTAF+zC8gOZ4x7D9wCXFA3CIin\\\\\\\\\\\\\\\/BYdzSaznXYEV\\\\\\\\\\\\\\\/phe6dJ1W0zTHu53eWX7XWJC4y9AKPXWD6Rzw\\\\\\\\\\\\\\\/CtspmGcgDzzDRAgorJvuS4gcbAPvk+AZdWYpzBh\\\\\\\\\\\\\\\/W2LboAYLsf8w9nR990TxvmiT2nuQIHP8\\\\\\\\\\\\\\\/YQePMWXehKfdMcP4rM674sMZRGFVkZtt+kUk9i3iP1CX5vz0OqOFdENlxDHESvQeYwU77Gk+ha1v83W90+9D7ViPNrYpC35jgXLhkypHw\\\\\\\\\\\\\\\/05AZCPT\\\\\\\\\\\\\\\/jk8YzaT5J66cQk5+c9De1pTyFERfuvZfXVqsKW+bYQ\\\\\\\\\\\\\\\/rCxT9vGZOQIkCCFoovMCvI0Zu7oI9eN2dqEfK312haKAiDVHvhv1ooMjghYBvRCizw2xuw64aN4TjdOO9N0+zRuHAfP07cByc0ciWuHxZenvvtKMBpfJewqLt5W30aRtunlyVXY01UB7+J4EApaXd7GFmmhO+63G+9LnQifurnWxOWh04EBFgmS0MTzC3zAfMqjkknLlh9Yg4C8811mX+EhlncOskqyM\\\\\\\\\\\\\\\/jHbhL0q2uHrdFjb5OxAtKVOrdvaCo7DbfBNEP+7KIHBa1IGfaDNIVOY1Hj9CgdUNPhTsr+PkH1u+foC0T\\\\\\\\\\\\\\\/uJMjIpACRPiTq\\\\\\\\\\\\\\\/aEJVlSLntaVyyI9X85ywUdWV1IrY4iN2ybrngbbU70ufbCbIAyGfgySZFgcYCXwXgPxWNjlS8p9Xk3QXL6DdIBTLJgEhTrla3g47+C\\\\\\\\\\\\\\\/wOPqLmGmquxMUOHBHzAYEz6ygWRrqtGe557l5d\\\\\\\\\\\\\\\/HHHePKszdPAL4B4CG9l2+70yerNMcAUvRp8G2oF0WHlrrPLea3jtAIbSGoOkkHYThoP9x8GvmW3J\\\\\\\\\\\\\\\/yo0YW7FfSR8zOOYgXHhEbznz6Q+yLNvLRaYOhO+4GHY7v1dlm6pg1FQvw0WB+ehbUz0urznxKXlkLbjZwjkjh4Q4E\\\\\\\\\\\\\\\/2Kikv5dkjrYFvCuxlan0s0WWzSLMTa6zIWm5MA3uihxETkAjEeZeEOTSo4K\\\\\\\\\\\\\\\/PpqMk+HBMz15le8rpTIHONNqcgNdXqpEASR04GPdbRil6jfGj78vK2LA5Co+n2jWtUlYwS0Dm51dS696M9A3aPniOvn56o5u15YtoXwVZB6hEDrS7CdaZKrQRm8NQiOziZHBbgVzgVJFp7u0oEIuwDVc7+vURkDUgDrkM2v2jjeRdUDocTYM+r9UxLwdOn2FHcB1BAX7TXJ6dZzCQ0qqylPybUdCyvGafoZ3ASyDrOGiKqtmsxjQfw+6HDL8\\\\\\\\\\\\\\\/1HnpIHkP9cWlPAOsFmt8qNpYcZJ0lxRn0h4rxFev+MOn2jEoO1sw7wrHgNgqUkuqsXm+VwZ8xqirewUJaJ9EqUwWG9hzT98LMugTlU4NslI2l9hQ==\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022JLAnUxP3bDgmRwZK54clvA==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u0022fc2e18f2149e966ddfd10361945388685cdbccdd72b559b942cd0a9b1128e926\\u0022}\u0022},\u0022bmjj\u0022:{\u0022show_corresp\u0022:false},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1,\u0022sites\\\/default\\\/modules\\\/jnl_template_bmjj\\\/plugins\\\/content_types\\\/js\\\/bmjj-contributors.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__XqNETqO2KISUuux0IjZeixOTFnSk20iJyWcdyjFvJv0__V5XKdmT7SKbPMZ3oiYeZn3IKAzRNs6WzDcLxN472J6o__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-art-info\u0022\u003E\u003Cdiv class=\u0022panel-display highwire-1col-stacked-layout\u0022\u003E\n\t  \u003Cdiv class=\u0022panel-row-wrapper panel-row-first clearfix\u0022\u003E\n\t\t\n\t\t\u003Cdiv class=\u0022top-wrapper\u0022\u003E\n\t\t\t\u003Cdiv class=\u0022panel-panel panel-region-top\u0022\u003E\n\t\t\t  \u003Cdiv class=\u0022inside\u0022\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-article-crossmark\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003C!-- Start CrossMark Snippet v2.0 --\u003E\n    \u003Ca data-target=\u0022crossmark\u0022 class=\u0022crossmark-square\u0022\u003E\u003Cimg src=\u0022https:\/\/crossmark-cdn.crossref.org\/widget\/v2.0\/logos\/CROSSMARK_Color_square.svg\u0022 alt=\u0022\u0022\u003E\u003C\/a\u003E\n    \u003Cdiv id=\u0022crossmark-dialog\u0022 style=\u0022display: none;\u0022 title=\u0022\u0022\u003E\n    \u003C!-- the external CrossMark data is loaded inside this iframe --\u003E\n    \u003Ciframe id=\u0022crossmark-dialog-frame\u0022\u003E\u003C\/iframe\u003E\n    \u003C\/div\u003E\n    \u003C!-- End CrossMark Snippet --\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-bmjj-contributors author-ids col-narrow-12\u0022\u003E\n  \n        \u003Ch3 class=\u0022pane-title\u0022\u003EAuthors\u003C\/h3\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022field field-name-field-highwire-a-contributors field-type-text field-label-hidden\u0022\u003E\u003Cdiv class=\u0022field-items\u0022\u003E\u003Cdiv class=\u0022field-item even\u0022\u003E\u003Cdiv class=\u0022highwire-list-wrapper\u0022\u003E\u003Cdiv class=\u0022highwire-list\u0022\u003E\u003Cul class=\u0022highwire-contributors-list single-contrib\u0022\u003E\u003Cli class=\u0022first last odd\u0022\u003E\u003Cspan class=\u0022nlm-given-names\u0022\u003ERongyu\u003C\/span\u003E \u003Cspan class=\u0022nlm-surname\u0022\u003EZhang\u003C\/span\u003E \u003Cspan class=\u0022nlm-aff\u0022\u003EInstitute for Systems Biology, University of Washington, Seattle, WA, USA\u003C\/span\u003E \u003Ca href=\u0022\/lookup\/external-ref?access_num=Zhang%20R\u0026amp;link_type=AUTHORSEARCH\u0022 target=\u0022_blank\u0022 class=\u0022authour-link\u0022 data-icon-position=\u0022\u0022 data-hide-link-title=\u00220\u0022\u003EPubMed articles\u003C\/a\u003E\u003Ca href=\u0022\/lookup\/google-scholar?author%5B0%5D=%22author%3ARongyu%20Zhang%22\u0026amp;gs_type=author\u0022 target=\u0022_blank\u0022 class=\u0022authour-link\u0022 data-icon-position=\u0022\u0022 data-hide-link-title=\u00220\u0022\u003EGoogle scholar articles\u003C\/a\u003E\u003C\/li\u003E\u003C\/ul\u003E\u003C\/div\u003E\u003C\/div\u003E\u003C\/div\u003E\u003C\/div\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n\t\t\t\u003C\/div\u003E\n\t\t\u003C\/div\u003E\n\t\n\t\u003C\/div\u003E \u003C!-- \/.panel-row-wrapper --\u003E\t\n\t  \n  \u003Cdiv class=\u0022panel-row-wrapper clearfix\u0022\u003E\n\t\t\n\t\t\u003Cdiv class=\u0022content-wrapper\u0022\u003E\n\t\t\t\u003Cdiv class=\u0022panel-panel panel-region-content\u0022\u003E\n\t\t\t  \u003Cdiv class=\u0022inside\u0022\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-article-citation\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ECitation\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022highwire-article-citation highwire-citation-type-highwire-article node51287\u0022 data-node-nid=\u002251287\u0022 id=\u0022node-51287--285657137\u0022 data-pisa=\u0022jitc;11\/Suppl_2\/A1799\u0022 data-pisa-master=\u0022jitc;jitc-2023-SITC2023.0442-O\u0022 data-apath=\u0022\/jitc\/11\/Suppl_2\/A1799.atom\u0022\u003E\u003Cdiv class=\u0022highwire-cite highwire-cite-highwire-article highwire-citation-v1-cp clearfix bmjj-article-citation\u0022\u003E\n  \n  \n    \t\u003Cdiv class=\u0022highwire-cite-authors\u0022\u003E\u003Cspan class=\u0022highwire-citation-authors\u0022\u003E\u003Cspan class=\u0022highwire-citation-author first\u0022 data-delta=\u00220\u0022\u003E\u003Cspan class=\u0022nlm-surname\u0022\u003EZhang\u003C\/span\u003E R\u003C\/span\u003E\u003C\/span\u003E\u003C\/div\u003E\n  \n      \u003Cdiv class=\u0022highwire-cite-title\u0022\u003E442-O\u0026acirc;\u0026#128;\u0026#133;Identifying cancer-specific T cells for immunotherapy through engineered proteins\u003C\/div\u003E  \n      \n    \t\u003Cdiv class=\u0022highwire-cite-metadata bmjj-citation-metadata\u0022\u003E\u003Cspan class=\u0022highwire-cite-metadata-journal highwire-cite-metadata\u0022\u003EJournal for ImmunoTherapy of Cancer \u003C\/span\u003E\u003Cspan class=\u0022highwire-cite-metadata-year highwire-cite-metadata\u0022\u003E2023;\u003C\/span\u003E\u003Cspan class=\u0022highwire-cite-metadata-volume highwire-cite-metadata\u0022\u003E11:\u003C\/span\u003E\u003Cspan class=\u0022highwire-cite-metadata-doi highwire-cite-metadata\u0022\u003E\u003Cspan class=\u0022label\u0022\u003Edoi:\u003C\/span\u003E 10.1136\/jitc-2023-SITC2023.0442-O \u003C\/span\u003E\u003C\/div\u003E\n  \n  \n  \n\u003C\/div\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-mini pane-jnl-template-bmjj-art-pub-history\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panel-display highwire-1col-stacked-layout\u0022 id=\u0022mini-panel-jnl_template_bmjj_art_pub_history\u0022\u003E\n\t  \n  \u003Cdiv class=\u0022panel-row-wrapper clearfix\u0022\u003E\n\t\t\n\t\t\u003Cdiv class=\u0022content-wrapper\u0022\u003E\n\t\t\t\u003Cdiv class=\u0022panel-panel panel-region-content\u0022\u003E\n\t\t\t  \u003Cdiv class=\u0022inside\u0022\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-pubdate bmjj-pub-date\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022field field-name-field-highwire-a-epubdate field-type-datetime field-label-inline clearfix\u0022\u003E\u003Cdiv class=\u0022field-label\u0022\u003EOnline issue publication\u0026nbsp;\u003C\/div\u003E\u003Cdiv class=\u0022field-items\u0022\u003E\u003Cdiv class=\u0022field-item even\u0022\u003E\u003Cspan class=\u0022date-display-single\u0022\u003EDecember 18, 2023\u003C\/span\u003E\u003C\/div\u003E\u003C\/div\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n\t\t\t\u003C\/div\u003E\n\t\t\u003C\/div\u003E\n\t\n\t\u003C\/div\u003E \u003C!-- \/.panel-row-wrapper --\u003E\t\n\t\n\t\u003C\/div\u003E\n\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content pane-highwire-permission-link\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-d5e9ecaa-460b-40c1-87fb-0dbcbc3a749d\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-d5e9ecaa-460b-40c1-87fb-0dbcbc3a749d\u0022 data-pid=\u0022new-d5e9ecaa-460b-40c1-87fb-0dbcbc3a749d\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-copyright\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ECopyright information\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022field field-name-field-highwire-copyright field-type-text field-label-hidden\u0022\u003E\u003Cdiv class=\u0022field-items\u0022\u003E\u003Cdiv class=\u0022field-item even\u0022\u003E\u003Cspan class=\u0022nlm-copyright-statement\u0022 data-hwp-id=\u0022copyright-statement-1\u0022\u003E\u0026Acirc;\u0026copy; Author(s) (or their employer(s)) 2023. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.\u003C\/span\u003E \u003Cspan class=\u0022nlm-license\u0022 data-license-type=\u0022open-access\u0022 data-xlink-href=\u0022http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/\u0022 data-hwp-id=\u0022license-1\u0022\u003E\u003Cspan class=\u0022ali-license_ref\u0022 data-start_date=\u00222023-10-24\u0022\u003E\u003Ca href=\u0022http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/\u0022\u003Ehttp:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/\u003C\/a\u003E\u003C\/span\u003E\u003Cspan class=\u0022nlm-p\u0022 data-hwp-id=\u0022p-1\u0022\u003EThis is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See \u003Ca class=\u0022nlm-ext-link\u0022 data-l-rel=\u0022related\u0022 data-l-ref-type=\u0022uri\u0022 data-l-ref=\u0022http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/\u0022 data-ext-link-type=\u0022uri\u0022 data-xlink-href=\u0022http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/\u0022 data-hwp-id=\u0022ext-link-1\u0022 href=\u0022http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/\u0022\u003Ehttp:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/\u003C\/a\u003E.\u003C\/span\u003E\u003C\/span\u003E\u003C\/div\u003E\u003C\/div\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n\t\t\t\u003C\/div\u003E\n\t\t\u003C\/div\u003E\n\t\n\t\u003C\/div\u003E \u003C!-- \/.panel-row-wrapper --\u003E\t\n\t\n\t\u003C\/div\u003E\n\n\u003C\/div\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022\/\/crossmark-cdn.crossref.org\/widget\/v2.0\/widget.js\u0022\u003E\u003C\/script\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}