{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_M8BsRY25PLDHBensqRcUs1nEubvHeoGn5HSxBrIWeZs.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-d5e9ecaa-460b-40c1-87fb-0dbcbc3a749d\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022VOhJNzNJkkFPZl7kNLJXwGVEpbzFfpcGK43wlFrIgbd2SgwYZeu2pNfY0merhDUovN6gMNvVs6VUJKubZQg3hjATc4QUSOAWx8PtjUUCYhrspNNPBAi0dtxhW9\\\\\\\\\\\\\\\/rgH1OTFrdKOopMFO2JKt7qk8AilMlN07\\\\\\\\\\\\\\\/u60BbWFiezElaMUlHc4i7eG+OwPQ6tsJVIJXNNMCo5EjIlwKl+wpWjYjB+BQBOWTWXgBsVE\\\\\\\\\\\\\\\/YsP1oR7ticFbHN2E\\\\\\\\\\\\\\\/QUErNf86DsG60OmPvTlCYloTQ8gWq9IO53uOxLEgvO0Wv+GAWjH9HP1WBDKjlQl0hdYeLR1F\\\\\\\\\\\\\\\/1kw\\\\\\\\\\\\\\\/jARFrDyteGJ4mSUd\\\\\\\\\\\\\\\/Focfhwm3iGKJ2X8iyT2r48DTC6l2X\\\\\\\\\\\\\\\/+a1+7d9nIaRAt4PILPGCo0ZId4bVOxZA23pikYHzMgJYB+AJCynKYjybtlKmIaMSYxsNaRZifadogZaSjRLTJr6GbeXeUgw52KwEprCq9kikhRxzYKKCcNd74KyrtNRbpiDUOiRJNsQKI2tmfgHXSA30fZJRzBVTI7Yh0c5iHg5fFnKf+VlvSOzl3J8WmQCZJRYVyEAvGNOdsmeyyo4bK9BDm4DZ8ej3uOorZkn2e5YdBx3zPt2VUB5wIJYKmuAMojDjQOrGaLFuCBnsUnGo44sg4Nlt9cKGHEWjOVo7jo9b7rn7v8QDbBqale3mBlYGJ2sKVz+Hxj89bxlkisFMoJ1ibON0Yzm+840tRN01c+tG29frX\\\\\\\\\\\\\\\/tOaKr2MRZuOpwjguuC7s3bAk7CHDzVThARsR+kj+ZAn77GrjQOq\\\\\\\\\\\\\\\/rPCwT1a6NznWWhU7uc0kOAjKBpnTdmTiPjt41sXj3tC0H6MJEoNwmz\\\\\\\\\\\\\\\/O73ca9E\\\\\\\\\\\\\\\/EdLXfAfYaTzvKbp+ZX8Bz3kzzim7RHM0kthb3cSvVhVFybEU7ZakSDo4KFQijNWZilD1cEF0XTrl8xh7hTEwb7a2IIQC\\\\\\\\\\\\\\\/0QRLT3JcpJ3dX90FlqVQgctCbO1VlsDoQhjIm3dv+p3Tt+ed94wRA2MI0DdfFclu25yASGsRs+M5qcsKNghupvo0EGExzTYs7IhJJ+O5eHcQu95035ZNnfQaP5HI0Wgw9XdbPE2NfC8eZqfKwb4bMCSND+Ei13qGrMw7G290re\\\\\\\\\\\\\\\/nX4YdljCVD6tZjCwCUGrkLMqzEYjze30vhgXuVN\\\\\\\\\\\\\\\/564H0+25xOVA1e9q8yMmOWbmvKCcvHNAzyXWtZRCikEqlsoLoxGWsPdtxbqjW3\\\\\\\\\\\\\\\/q8fdoAFI2o5a8\\\\\\\\\\\\\\\/kA76xiY20CwthRRhqjAAdUqujhqOQ2QFlb+V6Q9q9YYQjGPkLdNMWirfabAAHL0ouWYNiB0o7ugL6l6HinRwgRjNYhnqZnuStyyE2TN1PmhK9w5aq\\\\\\\\\\\\\\\/i1UvVlbaN\\\\\\\\\\\\\\\/oA9dpXSkI8fFr6+uroo\\\\\\\\\\\\\\\/r8fGY2VNbQGEwf7fTifr1DsGXPTvSuA\\\\\\\\\\\\\\\/2eVey1fFTYlceyty1I2Mpo62njLNmlW4JU9C9D\\\\\\\\\\\\\\\/Oqis3VOrr5AzNrg9tiuhJAsjS1Kbd9qdEiIfsbxGbS5G+\\\\\\\\\\\\\\\/0DmBu6kJLy8MZJWyropw67xxLeQge80u5\\\\\\\\\\\\\\\/fjTRV6Qd\\\\\\\\\\\\\\\/36kRr6QatiUz79qX3zvWumZ7jxc8Gwya8EG3xdN9WRb7IuEjUqEfxEY\\\\\\\\\\\\\\\/gkHoVHg6oJqs6MTdXst8ILo3L5WkBicPio3nkrQy+apq4uesSnQd6qayiAT3ydx5Y5LdWhlXl8tU2rv8gEpDPxvadteJdubKatHF96urcAuisGvQIYiJq1pTRhu0LjYhzSzVTEeiXuPihtXALstLPcR97J4e\\\\\\\\\\\\\\\/jfgBD7oMm3zpY+HLCSjARFe6eEbd8MRPFU0Cqu29\\\\\\\\\\\\\\\/Hlh+fx\\\\\\\\\\\\\\\/SkT0pb2Y6h3qlsGM4PFWT\\\\\\\\\\\\\\\/exTduRH6rXxL5EOu9pSm4qGizCCl59TI3JtOAdyATv3eDQCDjUM03ayOstAeAYgFIVXG0VUFCv3GZnRUDmH5Zxxy5RbLD3AkfSepFSzDGI+TE0oeiZknHYBNkelPHgfDOIycnKoVx5Gjz7L37BXjDZASVE2KRM9tYncGTBAhqFF5fN4\\\\\\\\\\\\\\\/NrhbLDnTAqh5a1ZQG1QP\\\\\\\\\\\\\\\/UlG40Yi10BZZy\\\\\\\\\\\\\\\/Vj08Va9Qam6wd9IiBL0DTz3S5HINXonY0tUL9gY0xvA9dL1jWw7xcmbxws04dc6z20D9UkY75W8rpbDJ0v2Y03tsnhyzvcfDAgeeWzb5\\\\\\\\\\\\\\\/sVDDXRGnt1UveeVVOW8awRwV0Effhj5cS59DthpCoyF5T7375\\\\\\\\\\\\\\\/dhUEUwiRciv9o5TX8eHAzRy1hNDcbFStRmk2dldK6JUvtJro\\\\\\\\\\\\\\\/pQMhPE1pf0zgNzhtH3lFGs0MiQz9djcxotZmeVF0Zh5B5vYl+eArK+HOX8jz3kHlOqu34p2L5arImox9ZhNoGeO3uxJq21opUGwyo18m2vPrCJk5IM4S3yM8wOmtvjLH9wftizwC9D\\\\\\\\\\\\\\\/k8QK0qEygrMCbaor5\\\\\\\\\\\\\\\/\\\\\\\\\\\\\\\/5wA0ve3KyVIlonEx7O8UnYsl6i5IIzVWTxQ8R60wH4OKhbwifC+hBlcph+KNdpInSiFHK7YGO964GSu\\\\\\\\\\\\\\\/trdIFuLv4BQVgv4CuwJMph6Pjj8T6ZCSNsU8qAdjHVL9PRM6HHkmeC0S9Lg5jlElSV\\\\\\\\\\\\\\\/wEkMhA8djqYKpxnnYZI\\\\\\\\\\\\\\\/0HfV2kJsKqYSnTweq5ZbRhwT6OkeS8PJcSQVaABRVN7DiIWKjUZ8LOPkEiVFlqv3\\\\\\\\\\\\\\\/knIAmqXR4eyNAX0ADiLmsZl\\\\\\\\\\\\\\\/dl7zO5IaFgP3dl0MWJX9L7tMO3eX9ygnUXeTvNfvFIHvFL+afIp75uNu\\\\\\\\\\\\\\\/y6mmK11JC81TjhL6NC9Eli+rWTxsQcrP9wnxm3kVU9XFclZAD2t7b2hqYAxngUjN09MgjlmcUccMBeJDBb0NJjLSQaLOzoXUX1iohvr93p\\\\\\\\\\\\\\\/yH9EyBNCku4BTsMZOR19NB+9d+77qBvP\\\\\\\\\\\\\\\/j2SuyONvLr90yR4TmXgRuakix3jwnenwaiElTkbcjS0jp6iSYCFj9w==\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u00223zS6M71pcEdH9\\\\\\\\\\\\\\\/igWNsT4A==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u0022a7146dc6dc439e53ed433ebe8cc53589063557c3553a50ebcb8983890e59a568\\u0022}\u0022},\u0022bmjj\u0022:{\u0022show_corresp\u0022:false},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1,\u0022sites\\\/default\\\/modules\\\/jnl_template_bmjj\\\/plugins\\\/content_types\\\/js\\\/bmjj-contributors.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__XqNETqO2KISUuux0IjZeixOTFnSk20iJyWcdyjFvJv0__V5XKdmT7SKbPMZ3oiYeZn3IKAzRNs6WzDcLxN472J6o__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-art-info\u0022\u003E\u003Cdiv class=\u0022panel-display highwire-1col-stacked-layout\u0022\u003E\n\t  \u003Cdiv class=\u0022panel-row-wrapper panel-row-first clearfix\u0022\u003E\n\t\t\n\t\t\u003Cdiv class=\u0022top-wrapper\u0022\u003E\n\t\t\t\u003Cdiv class=\u0022panel-panel panel-region-top\u0022\u003E\n\t\t\t  \u003Cdiv class=\u0022inside\u0022\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-article-crossmark\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003C!-- Start CrossMark Snippet v2.0 --\u003E\n    \u003Ca data-target=\u0022crossmark\u0022 class=\u0022crossmark-square\u0022\u003E\u003Cimg src=\u0022https:\/\/crossmark-cdn.crossref.org\/widget\/v2.0\/logos\/CROSSMARK_Color_square.svg\u0022 alt=\u0022\u0022\u003E\u003C\/a\u003E\n    \u003Cdiv id=\u0022crossmark-dialog\u0022 style=\u0022display: none;\u0022 title=\u0022\u0022\u003E\n    \u003C!-- the external CrossMark data is loaded inside this iframe --\u003E\n    \u003Ciframe id=\u0022crossmark-dialog-frame\u0022\u003E\u003C\/iframe\u003E\n    \u003C\/div\u003E\n    \u003C!-- End CrossMark Snippet --\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-bmjj-contributors author-ids col-narrow-12\u0022\u003E\n  \n        \u003Ch3 class=\u0022pane-title\u0022\u003EAuthors\u003C\/h3\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022field field-name-field-highwire-a-contributors field-type-text field-label-hidden\u0022\u003E\u003Cdiv class=\u0022field-items\u0022\u003E\u003Cdiv class=\u0022field-item even\u0022\u003E\u003Cdiv class=\u0022highwire-list-wrapper\u0022\u003E\u003Cdiv class=\u0022highwire-list\u0022\u003E\u003Cul class=\u0022highwire-contributors-list double-contrib\u0022\u003E\u003Cli class=\u0022first odd\u0022\u003E\u003Cspan class=\u0022nlm-given-names\u0022\u003EJohn C\u003C\/span\u003E \u003Cspan class=\u0022nlm-surname\u0022\u003EHancock\u003C\/span\u003E \u003Cspan class=\u0022nlm-aff\u0022\u003ENational Cancer Institute, Bethesda, MD, USA\u003C\/span\u003E \u003Ca href=\u0022\/lookup\/external-ref?access_num=Hancock%20JC\u0026amp;link_type=AUTHORSEARCH\u0022 target=\u0022_blank\u0022 class=\u0022authour-link\u0022 data-icon-position=\u0022\u0022 data-hide-link-title=\u00220\u0022\u003EPubMed articles\u003C\/a\u003E\u003Ca href=\u0022\/lookup\/google-scholar?author%5B0%5D=%22author%3AJohn%20C%20Hancock%22\u0026amp;gs_type=author\u0022 target=\u0022_blank\u0022 class=\u0022authour-link\u0022 data-icon-position=\u0022\u0022 data-hide-link-title=\u00220\u0022\u003EGoogle scholar articles\u003C\/a\u003E\u003C\/li\u003E\u003Cli class=\u0022last even\u0022\u003E\u003Cspan class=\u0022nlm-given-names\u0022\u003EMark\u003C\/span\u003E \u003Cspan class=\u0022nlm-surname\u0022\u003EGilbert\u003C\/span\u003E \u003Cspan class=\u0022nlm-aff\u0022\u003ENational Cancer Institute, Bethesda, MD, USA\u003C\/span\u003E \u003Ca href=\u0022\/lookup\/external-ref?access_num=Gilbert%20M\u0026amp;link_type=AUTHORSEARCH\u0022 target=\u0022_blank\u0022 class=\u0022authour-link\u0022 data-icon-position=\u0022\u0022 data-hide-link-title=\u00220\u0022\u003EPubMed articles\u003C\/a\u003E\u003Ca href=\u0022\/lookup\/google-scholar?author%5B0%5D=%22author%3AMark%20Gilbert%22\u0026amp;gs_type=author\u0022 target=\u0022_blank\u0022 class=\u0022authour-link\u0022 data-icon-position=\u0022\u0022 data-hide-link-title=\u00220\u0022\u003EGoogle scholar articles\u003C\/a\u003E\u003C\/li\u003E\u003C\/ul\u003E\u003C\/div\u003E\u003C\/div\u003E\u003C\/div\u003E\u003C\/div\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n\t\t\t\u003C\/div\u003E\n\t\t\u003C\/div\u003E\n\t\n\t\u003C\/div\u003E \u003C!-- \/.panel-row-wrapper --\u003E\t\n\t  \n  \u003Cdiv class=\u0022panel-row-wrapper clearfix\u0022\u003E\n\t\t\n\t\t\u003Cdiv class=\u0022content-wrapper\u0022\u003E\n\t\t\t\u003Cdiv class=\u0022panel-panel panel-region-content\u0022\u003E\n\t\t\t  \u003Cdiv class=\u0022inside\u0022\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-article-citation\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ECitation\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022highwire-article-citation highwire-citation-type-highwire-article node49629\u0022 data-node-nid=\u002249629\u0022 id=\u0022node-49629--2965120898\u0022 data-pisa=\u0022jitc;11\/Suppl_1\/A1641\u0022 data-pisa-master=\u0022jitc;jitc-2023-SITC2023.1477\u0022 data-apath=\u0022\/jitc\/11\/Suppl_1\/A1641.atom\u0022\u003E\u003Cdiv class=\u0022highwire-cite highwire-cite-highwire-article highwire-citation-v1-cp clearfix bmjj-article-citation\u0022\u003E\n  \n  \n    \t\u003Cdiv class=\u0022highwire-cite-authors\u0022\u003E\u003Cspan class=\u0022highwire-citation-authors\u0022\u003E\u003Cspan class=\u0022highwire-citation-author first\u0022 data-delta=\u00220\u0022\u003E\u003Cspan class=\u0022nlm-surname\u0022\u003EHancock\u003C\/span\u003E JC\u003C\/span\u003E, \u003Cspan class=\u0022highwire-citation-author\u0022 data-delta=\u00221\u0022\u003E\u003Cspan class=\u0022nlm-surname\u0022\u003EGilbert\u003C\/span\u003E M\u003C\/span\u003E\u003C\/span\u003E\u003C\/div\u003E\n  \n      \u003Cdiv class=\u0022highwire-cite-title\u0022\u003E1477\u0026acirc;\u0026#128;\u0026#133;Neuronal modulation of myeloid cells in glioblastoma\u003C\/div\u003E  \n      \n    \t\u003Cdiv class=\u0022highwire-cite-metadata bmjj-citation-metadata\u0022\u003E\u003Cspan class=\u0022highwire-cite-metadata-journal highwire-cite-metadata\u0022\u003EJournal for ImmunoTherapy of Cancer \u003C\/span\u003E\u003Cspan class=\u0022highwire-cite-metadata-year highwire-cite-metadata\u0022\u003E2023;\u003C\/span\u003E\u003Cspan class=\u0022highwire-cite-metadata-volume highwire-cite-metadata\u0022\u003E11:\u003C\/span\u003E\u003Cspan class=\u0022highwire-cite-metadata-doi highwire-cite-metadata\u0022\u003E\u003Cspan class=\u0022label\u0022\u003Edoi:\u003C\/span\u003E 10.1136\/jitc-2023-SITC2023.1477 \u003C\/span\u003E\u003C\/div\u003E\n  \n  \n  \n\u003C\/div\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-mini pane-jnl-template-bmjj-art-pub-history\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panel-display highwire-1col-stacked-layout\u0022 id=\u0022mini-panel-jnl_template_bmjj_art_pub_history\u0022\u003E\n\t  \n  \u003Cdiv class=\u0022panel-row-wrapper clearfix\u0022\u003E\n\t\t\n\t\t\u003Cdiv class=\u0022content-wrapper\u0022\u003E\n\t\t\t\u003Cdiv class=\u0022panel-panel panel-region-content\u0022\u003E\n\t\t\t  \u003Cdiv class=\u0022inside\u0022\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-pubdate bmjj-pub-date\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022field field-name-field-highwire-a-epubdate field-type-datetime field-label-inline clearfix\u0022\u003E\u003Cdiv class=\u0022field-label\u0022\u003EOnline issue publication\u0026nbsp;\u003C\/div\u003E\u003Cdiv class=\u0022field-items\u0022\u003E\u003Cdiv class=\u0022field-item even\u0022\u003E\u003Cspan class=\u0022date-display-single\u0022\u003ENovember 02, 2023\u003C\/span\u003E\u003C\/div\u003E\u003C\/div\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n\t\t\t\u003C\/div\u003E\n\t\t\u003C\/div\u003E\n\t\n\t\u003C\/div\u003E \u003C!-- \/.panel-row-wrapper --\u003E\t\n\t\n\t\u003C\/div\u003E\n\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content pane-highwire-permission-link\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-d5e9ecaa-460b-40c1-87fb-0dbcbc3a749d\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-d5e9ecaa-460b-40c1-87fb-0dbcbc3a749d\u0022 data-pid=\u0022new-d5e9ecaa-460b-40c1-87fb-0dbcbc3a749d\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-copyright\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ECopyright information\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022field field-name-field-highwire-copyright field-type-text field-label-hidden\u0022\u003E\u003Cdiv class=\u0022field-items\u0022\u003E\u003Cdiv class=\u0022field-item even\u0022\u003E\u003Cspan class=\u0022nlm-copyright-statement\u0022 data-hwp-id=\u0022copyright-statement-1\u0022\u003E\u0026Acirc;\u0026copy; Author(s) (or their employer(s)) 2023. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.\u003C\/span\u003E \u003Cspan class=\u0022nlm-license\u0022 data-license-type=\u0022open-access\u0022 data-xlink-href=\u0022http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/\u0022 data-hwp-id=\u0022license-1\u0022\u003E\u003Cspan class=\u0022ali-license_ref\u0022 data-start_date=\u00222023-10-21\u0022\u003E\u003Ca href=\u0022http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/\u0022\u003Ehttp:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/\u003C\/a\u003E\u003C\/span\u003E\u003Cspan class=\u0022nlm-p\u0022 data-hwp-id=\u0022p-1\u0022\u003EThis is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See \u003Ca class=\u0022nlm-ext-link\u0022 data-l-rel=\u0022related\u0022 data-l-ref-type=\u0022uri\u0022 data-l-ref=\u0022http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/\u0022 data-ext-link-type=\u0022uri\u0022 data-xlink-href=\u0022http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/\u0022 data-hwp-id=\u0022ext-link-1\u0022 href=\u0022http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/\u0022\u003Ehttp:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/\u003C\/a\u003E.\u003C\/span\u003E\u003C\/span\u003E\u003C\/div\u003E\u003C\/div\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n\t\t\t\u003C\/div\u003E\n\t\t\u003C\/div\u003E\n\t\n\t\u003C\/div\u003E \u003C!-- \/.panel-row-wrapper --\u003E\t\n\t\n\t\u003C\/div\u003E\n\n\u003C\/div\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022\/\/crossmark-cdn.crossref.org\/widget\/v2.0\/widget.js\u0022\u003E\u003C\/script\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}