{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_M8BsRY25PLDHBensqRcUs1nEubvHeoGn5HSxBrIWeZs.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-d5e9ecaa-460b-40c1-87fb-0dbcbc3a749d\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022bg4+IlOyGyyQC0KtcZd1iSohdppKxZpGPF5FI7P9FFOXlB0cCGAXQ\\\\\\\\\\\\\\\/LOS\\\\\\\\\\\\\\\/dH9Ku68s1W1VEHDzGaAnhWkyaLFtbRYD5G3B68wfCM+tJbsz2w\\\\\\\\\\\\\\\/8IU69ZqwPLikqRPO5Jac17DUSnH3ylUN5AD9SckzDDmfF3Amraz4GrkevU+\\\\\\\\\\\\\\\/2jfP2dPOmfrm3334qQLCSs+lSyV6FqR34RotdE8v7utn9asqdFTX6F4pD9wiiFEyTJnlLvZ+P29o\\\\\\\\\\\\\\\/RpeD\\\\\\\\\\\\\\\/RoIos5Qj6dFce3lDYnQNr3DlVEPwXN17orxG69GzI0BVyYK1dbofzWFFB1nGWJ8+BIKDC9209Rj5iMZdeIp41Qytx4DnLlFqNnjMMOp4u6Hdk1cisxr4Yl8wIQZKDyLEYYtjKyxFycR9f8KjnhgY1BNcOiP19yCpUU1wGu1\\\\\\\\\\\\\\\/XTpvShlc9Y5QzTrhi4\\\\\\\\\\\\\\\/INuzr1\\\\\\\\\\\\\\\/eLKD\\\\\\\\\\\\\\\/mtSxG5A3w8cOYcOqmdjOByQ7MgM6ooARRHVoSKco68EcWoWQgCjqn2YXgMFT7YTdblP0Ihl+Lk+ywOuCHpXknPWDhjH1IiDpGd7BTmY7c3QItilK4IgOWaV6pC663AmdVpphbthEFIXM9wCE5H+ehwhZ\\\\\\\\\\\\\\\/y5fiMTylPRreDsYbSXcpxVgUmqS\\\\\\\\\\\\\\\/1uL7jY1oQypi2fsdEUIN\\\\\\\\\\\\\\\/JnMGK\\\\\\\\\\\\\\\/9zta4qD8IpiRV49S76OxOxhyDPg6zJ7Rkwk1U\\\\\\\\\\\\\\\/\\\\\\\\\\\\\\\/j6Au9LYdyJOC66gUVsn9pEyBEX5xKLYl3ijzpfN72SdwfmwJ\\\\\\\\\\\\\\\/5TRxEd4ktlpBl+geW3X1JNv8bm9YRjI+j3hujvg0S5GcYyVz1151vRvQI1dtXpsrAXgEL8iVn9RlTUvMamUEpyI6yLzrRu2bIkVSsgCi\\\\\\\\\\\\\\\/OsqEOtuzTXkv5lnathp465Oe1X0jbK4wEa6cvkws2l5ZPgCpvsUPt0y\\\\\\\\\\\\\\\/yhiHVkCD6\\\\\\\\\\\\\\\/QqodQEhZRTp7u8qF9axoxCOEtHYFyAYFkf\\\\\\\\\\\\\\\/RETEjvBzE7yQGzk5xp\\\\\\\\\\\\\\\/zUpJU82kjVYooEiDv07QFdxflu0vtoioUiQVEVvBM5NI+IllH1NyfsivNjHLtjGbAaZe4rM\\\\\\\\\\\\\\\/whoXjaSpR90CoZBxLmlZIIGlqrjgrc3Loe9bFtwM90Y6w7\\\\\\\\\\\\\\\/zdQseeXJfOAHN\\\\\\\\\\\\\\\/iEduH2l0OKeJMtqkCpVObo2uvKlKtkvDya+D1VMQsExeM1RU8y7bVEoU657YY+Z\\\\\\\\\\\\\\\/jdGJj6OEierPxRzBhooZh8uG5czOyryyYEd7WqCsijKnkHhVbnLmWlpfIvZvvJLOl44e\\\\\\\\\\\\\\\/cORTyd0U\\\\\\\\\\\\\\\/NEGAtUJbNH4k1ZFvqkaaiMrw9xSaA6ZxAydovE58fRjt3Sg5CN2oEMxdBrcc89Ai+NlfpWrhBglfgz+7+RQdrEhzgnZv19eqJ\\\\\\\\\\\\\\\/oyg8bXJf2j\\\\\\\\\\\\\\\/osHy6R\\\\\\\\\\\\\\\/gNe4R5rcpS87C9+CSmm+EZgXtFBRcrHcXWgbv\\\\\\\\\\\\\\\/1xKJtTE7J1e2w1tUn\\\\\\\\\\\\\\\/WQYo9WMGYBNd1Hs2q0BHEF2kNNFIJPgsYzddKapGIkEdrO2rf6s+hT2pWKrsB8nMakqFglsEjTCKKoKdqCtYorBxkBzGo5LWgILfDzWzhwIviid1\\\\\\\\\\\\\\\/9VgRyh+Uq2CmbI\\\\\\\\\\\\\\\/mLpzzQt55q6XwKd+06AFyuq06wuLj9Q\\\\\\\\\\\\\\\/2R80H0hMYjwSYavZz15I8hOZw+90LD\\\\\\\\\\\\\\\/3iEeC3q+q8iE+\\\\\\\\\\\\\\\/oH\\\\\\\\\\\\\\\/gl2S0guJtPa725PYUL4coDeU6vnVqLfGFF3iCxlwJIgKcj4txYftqS60865EPpx0dLbYtSxrFO3wbLcC0bBkSS1rnMlpqOgNxFHIDi8gn7pXsqsaHhOgQ0JSVnfVse5ReNpRK3N7xLfZ7dfVdeW\\\\\\\\\\\\\\\/Cu+LQ4JA1PsZJgGM\\\\\\\\\\\\\\\/z8zrrZKA0\\\\\\\\\\\\\\\/OSE8\\\\\\\\\\\\\\\/Df9hkq98dNlxiZz2SC1Q91kVpDilaksegCz89v9gsOPfC7YquVKeyWsqFj3LaSZtup160cCxzjoe7cf+9nngT1ZjWi7\\\\\\\\\\\\\\\/p\\\\\\\\\\\\\\\/CcU3cGthDZ8NrZb3h6cQHlEK7YxG3dGkrUHeZmpVU2E1BRcaU1N8pK9q7NmjnJFU\\\\\\\\\\\\\\\/6G4LST0ely0y\\\\\\\\\\\\\\\/mPf24Lt7Rk7u2cOP\\\\\\\\\\\\\\\/tFQsXMAmgQtFcgGxnEzHmXMShVkMpsI00x\\\\\\\\\\\\\\\/HpOXkGApnWaiJVpL4MZamPfzuGJCNmetGvQagyQ5AlLaAyW0dfZo6MISGseexemjFqHRKSAntM7WCidYMtgZ\\\\\\\\\\\\\\\/Dli\\\\\\\\\\\\\\\/stvjKxMV\\\\\\\\\\\\\\\/Em4yU9AcgnjRVrZ1zx9iQdOB\\\\\\\\\\\\\\\/FjRBw0I0pZWJGZp5cfCy6e1inxFQamztbuA9BvvneQUioLBKNnGmbjaZveZCZv5+3\\\\\\\\\\\\\\\/KFZjesxQDCTDYTsLvxPcKkU8LwiAWA+hKodMP1zAE4USAcR8lQzo1+pd41sCoiGbQJZf7bsntS+cIissr\\\\\\\\\\\\\\\/AapwbaIQtbOuRsJhmY+heNyWQ39OOZXv+YeVU8Y\\\\\\\\\\\\\\\/G6FZgQjieHTHzZQog9Nsfc0Z4Jjn7oLCeTeOELPq+uLwNpSARaClSHh8lO6Y46VPqvCXl60rrvJD\\\\\\\\\\\\\\\/pldJCrKNtGt+oNnObTm20yBlK7OyT2NlHDNn0azZ4hk4rbJuzDNAOH+IBqtbjeUoQ4tAVDHmpoua5I0Qug9QK\\\\\\\\\\\\\\\/JACssmWDylMMlDDIVlWY6eQGOqpF9Z+ZB4XGsrCKLZPYtBCA5kbqN1e9pFz3TmJQNPpMgcT4t8uehD0LFO+T5fx+RbV1zq6Oe7krSkmtTTLVI72VSEdlJNdcdMlsZGoepx3NxWLsWfVwVJTaBSEFVy6Ro3Cl0CnhpLlSJ13MLF8KqK3fOxowYZyYQcCSHsv6MFMVgyFlP6TV+RAuo\\\\\\\\\\\\\\\/0xTtLXRxhLNqiossb4HO3WZ7KBkEJFej3saC5hKS\\\\\\\\\\\\\\\/TM9X43VcyMtxK+lVmtGr1MPd9U\\\\\\\\\\\\\\\/UlAMgK0TlkPInN4p+OxfOIw+DUFeb5mM6iKHZ7nCbOTQjPH4PsFNyV9iiCJpQXIHqStto9uKnk\\\\\\\\\\\\\\\/bc7n0uBxo53Yn4liLcDf3lB+FzP2GiIjiy3dvpZpjjw9w==\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u00224MQO250b4O\\\\\\\\\\\\\\\/7\\\\\\\\\\\\\\\/3dhFYQ4sA==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u0022717828a1a89bc07577e4ec3b68e20b4be975ddd85bec2dd7c58f82ec14017aa9\\u0022}\u0022},\u0022bmjj\u0022:{\u0022show_corresp\u0022:false},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1,\u0022sites\\\/default\\\/modules\\\/jnl_template_bmjj\\\/plugins\\\/content_types\\\/js\\\/bmjj-contributors.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__XqNETqO2KISUuux0IjZeixOTFnSk20iJyWcdyjFvJv0__V5XKdmT7SKbPMZ3oiYeZn3IKAzRNs6WzDcLxN472J6o__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-art-info\u0022\u003E\u003Cdiv class=\u0022panel-display highwire-1col-stacked-layout\u0022\u003E\n\t  \u003Cdiv class=\u0022panel-row-wrapper panel-row-first clearfix\u0022\u003E\n\t\t\n\t\t\u003Cdiv class=\u0022top-wrapper\u0022\u003E\n\t\t\t\u003Cdiv class=\u0022panel-panel panel-region-top\u0022\u003E\n\t\t\t  \u003Cdiv class=\u0022inside\u0022\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-article-crossmark\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003C!-- Start CrossMark Snippet v2.0 --\u003E\n    \u003Ca data-target=\u0022crossmark\u0022 class=\u0022crossmark-square\u0022\u003E\u003Cimg src=\u0022https:\/\/crossmark-cdn.crossref.org\/widget\/v2.0\/logos\/CROSSMARK_Color_square.svg\u0022 alt=\u0022\u0022\u003E\u003C\/a\u003E\n    \u003Cdiv id=\u0022crossmark-dialog\u0022 style=\u0022display: none;\u0022 title=\u0022\u0022\u003E\n    \u003C!-- the external CrossMark data is loaded inside this iframe --\u003E\n    \u003Ciframe id=\u0022crossmark-dialog-frame\u0022\u003E\u003C\/iframe\u003E\n    \u003C\/div\u003E\n    \u003C!-- End CrossMark Snippet --\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-bmjj-contributors author-ids col-narrow-12\u0022\u003E\n  \n        \u003Ch3 class=\u0022pane-title\u0022\u003EAuthors\u003C\/h3\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022field field-name-field-highwire-a-contributors field-type-text field-label-hidden\u0022\u003E\u003Cdiv class=\u0022field-items\u0022\u003E\u003Cdiv class=\u0022field-item even\u0022\u003E\u003Cdiv class=\u0022highwire-list-wrapper\u0022\u003E\u003Cdiv class=\u0022highwire-list\u0022\u003E\u003Cul class=\u0022highwire-contributors-list multiple-contrib\u0022\u003E\u003Cli class=\u0022first odd\u0022\u003E\u003Cspan class=\u0022nlm-given-names\u0022\u003EDamieanus\u003C\/span\u003E \u003Cspan class=\u0022nlm-surname\u0022\u003EOchola\u003C\/span\u003E \u003Cspan class=\u0022nlm-aff\u0022\u003ESpanios, Houston, TX, USA\u003C\/span\u003E \u003Ca href=\u0022\/lookup\/external-ref?access_num=Ochola%20D\u0026amp;link_type=AUTHORSEARCH\u0022 target=\u0022_blank\u0022 class=\u0022authour-link\u0022 data-icon-position=\u0022\u0022 data-hide-link-title=\u00220\u0022\u003EPubMed articles\u003C\/a\u003E\u003Ca href=\u0022\/lookup\/google-scholar?author%5B0%5D=%22author%3ADamieanus%20Ochola%22\u0026amp;gs_type=author\u0022 target=\u0022_blank\u0022 class=\u0022authour-link\u0022 data-icon-position=\u0022\u0022 data-hide-link-title=\u00220\u0022\u003EGoogle scholar articles\u003C\/a\u003E\u003C\/li\u003E\u003Cli class=\u0022even\u0022\u003E\u003Cspan class=\u0022nlm-given-names\u0022\u003EHuckie Del\u003C\/span\u003E \u003Cspan class=\u0022nlm-surname\u0022\u003EMundo\u003C\/span\u003E \u003Cspan class=\u0022nlm-aff\u0022\u003ESpanios, Houston, TX, USA\u003C\/span\u003E \u003Ca href=\u0022\/lookup\/external-ref?access_num=Mundo%20HD\u0026amp;link_type=AUTHORSEARCH\u0022 target=\u0022_blank\u0022 class=\u0022authour-link\u0022 data-icon-position=\u0022\u0022 data-hide-link-title=\u00220\u0022\u003EPubMed articles\u003C\/a\u003E\u003Ca href=\u0022\/lookup\/google-scholar?author%5B0%5D=%22author%3AHuckie%20Del%20Mundo%22\u0026amp;gs_type=author\u0022 target=\u0022_blank\u0022 class=\u0022authour-link\u0022 data-icon-position=\u0022\u0022 data-hide-link-title=\u00220\u0022\u003EGoogle scholar articles\u003C\/a\u003E\u003C\/li\u003E\u003Cli class=\u0022odd\u0022\u003E\u003Cspan class=\u0022nlm-given-names\u0022\u003EBhuvanesh\u003C\/span\u003E \u003Cspan class=\u0022nlm-surname\u0022\u003EDave\u003C\/span\u003E \u003Cspan class=\u0022nlm-aff\u0022\u003ESpanios, Houston, TX, USA\u003C\/span\u003E \u003Ca href=\u0022\/lookup\/external-ref?access_num=Dave%20B\u0026amp;link_type=AUTHORSEARCH\u0022 target=\u0022_blank\u0022 class=\u0022authour-link\u0022 data-icon-position=\u0022\u0022 data-hide-link-title=\u00220\u0022\u003EPubMed articles\u003C\/a\u003E\u003Ca href=\u0022\/lookup\/google-scholar?author%5B0%5D=%22author%3ABhuvanesh%20Dave%22\u0026amp;gs_type=author\u0022 target=\u0022_blank\u0022 class=\u0022authour-link\u0022 data-icon-position=\u0022\u0022 data-hide-link-title=\u00220\u0022\u003EGoogle scholar articles\u003C\/a\u003E\u003C\/li\u003E\u003Cli class=\u0022last even\u0022\u003E\u003Cspan class=\u0022nlm-given-names\u0022\u003EPreethi\u003C\/span\u003E \u003Cspan class=\u0022nlm-surname\u0022\u003ESamuel\u003C\/span\u003E \u003Cspan class=\u0022nlm-aff\u0022\u003ESpanios, Houston, TX, USA\u003C\/span\u003E \u003Ca href=\u0022\/lookup\/external-ref?access_num=Samuel%20P\u0026amp;link_type=AUTHORSEARCH\u0022 target=\u0022_blank\u0022 class=\u0022authour-link\u0022 data-icon-position=\u0022\u0022 data-hide-link-title=\u00220\u0022\u003EPubMed articles\u003C\/a\u003E\u003Ca href=\u0022\/lookup\/google-scholar?author%5B0%5D=%22author%3APreethi%20Samuel%22\u0026amp;gs_type=author\u0022 target=\u0022_blank\u0022 class=\u0022authour-link\u0022 data-icon-position=\u0022\u0022 data-hide-link-title=\u00220\u0022\u003EGoogle scholar articles\u003C\/a\u003E\u003C\/li\u003E\u003C\/ul\u003E\u003C\/div\u003E\u003C\/div\u003E\u003C\/div\u003E\u003C\/div\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n\t\t\t\u003C\/div\u003E\n\t\t\u003C\/div\u003E\n\t\n\t\u003C\/div\u003E \u003C!-- \/.panel-row-wrapper --\u003E\t\n\t  \n  \u003Cdiv class=\u0022panel-row-wrapper clearfix\u0022\u003E\n\t\t\n\t\t\u003Cdiv class=\u0022content-wrapper\u0022\u003E\n\t\t\t\u003Cdiv class=\u0022panel-panel panel-region-content\u0022\u003E\n\t\t\t  \u003Cdiv class=\u0022inside\u0022\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-article-citation\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ECitation\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022highwire-article-citation highwire-citation-type-highwire-article node49301--3\u0022 data-node-nid=\u002249301\u0022 id=\u0022node-49301--417758642\u0022 data-pisa=\u0022jitc;11\/Suppl_1\/A149\u0022 data-pisa-master=\u0022jitc;jitc-2023-SITC2023.0131\u0022 data-apath=\u0022\/jitc\/11\/Suppl_1\/A149.atom\u0022\u003E\u003Cdiv class=\u0022highwire-cite highwire-cite-highwire-article highwire-citation-v1-cp clearfix bmjj-article-citation\u0022\u003E\n  \n  \n    \t\u003Cdiv class=\u0022highwire-cite-authors\u0022\u003E\u003Cspan class=\u0022highwire-citation-authors\u0022\u003E\u003Cspan class=\u0022highwire-citation-author first\u0022 data-delta=\u00220\u0022\u003E\u003Cspan class=\u0022nlm-surname\u0022\u003EOchola\u003C\/span\u003E D\u003C\/span\u003E, \u003Cspan class=\u0022highwire-citation-author\u0022 data-delta=\u00221\u0022\u003E\u003Cspan class=\u0022nlm-surname\u0022\u003EMundo\u003C\/span\u003E HD\u003C\/span\u003E, \u003Cspan class=\u0022highwire-citation-author\u0022 data-delta=\u00222\u0022\u003E\u003Cspan class=\u0022nlm-surname\u0022\u003EDave\u003C\/span\u003E B\u003C\/span\u003E\u003C\/span\u003E\u003Cspan class=\u0022citation-et\u0022\u003E, et al\u003C\/span\u003E\u003C\/div\u003E\n  \n      \u003Cdiv class=\u0022highwire-cite-title\u0022\u003E131\u0026acirc;\u0026#128;\u0026#133;Evaluating the presence and temporal distribution of immune components in matrigel-based sarcoma and gallbladder cancer patient derived tumoroids (PDTs) that have intact tumor microenvironment\u003C\/div\u003E  \n      \n    \t\u003Cdiv class=\u0022highwire-cite-metadata bmjj-citation-metadata\u0022\u003E\u003Cspan class=\u0022highwire-cite-metadata-journal highwire-cite-metadata\u0022\u003EJournal for ImmunoTherapy of Cancer \u003C\/span\u003E\u003Cspan class=\u0022highwire-cite-metadata-year highwire-cite-metadata\u0022\u003E2023;\u003C\/span\u003E\u003Cspan class=\u0022highwire-cite-metadata-volume highwire-cite-metadata\u0022\u003E11:\u003C\/span\u003E\u003Cspan class=\u0022highwire-cite-metadata-doi highwire-cite-metadata\u0022\u003E\u003Cspan class=\u0022label\u0022\u003Edoi:\u003C\/span\u003E 10.1136\/jitc-2023-SITC2023.0131 \u003C\/span\u003E\u003C\/div\u003E\n  \n  \n  \n\u003C\/div\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-mini pane-jnl-template-bmjj-art-pub-history\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panel-display highwire-1col-stacked-layout\u0022 id=\u0022mini-panel-jnl_template_bmjj_art_pub_history\u0022\u003E\n\t  \n  \u003Cdiv class=\u0022panel-row-wrapper clearfix\u0022\u003E\n\t\t\n\t\t\u003Cdiv class=\u0022content-wrapper\u0022\u003E\n\t\t\t\u003Cdiv class=\u0022panel-panel panel-region-content\u0022\u003E\n\t\t\t  \u003Cdiv class=\u0022inside\u0022\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-pubdate bmjj-pub-date\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022field field-name-field-highwire-a-epubdate field-type-datetime field-label-inline clearfix\u0022\u003E\u003Cdiv class=\u0022field-label\u0022\u003EOnline issue publication\u0026nbsp;\u003C\/div\u003E\u003Cdiv class=\u0022field-items\u0022\u003E\u003Cdiv class=\u0022field-item even\u0022\u003E\u003Cspan class=\u0022date-display-single\u0022\u003ENovember 02, 2023\u003C\/span\u003E\u003C\/div\u003E\u003C\/div\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n\t\t\t\u003C\/div\u003E\n\t\t\u003C\/div\u003E\n\t\n\t\u003C\/div\u003E \u003C!-- \/.panel-row-wrapper --\u003E\t\n\t\n\t\u003C\/div\u003E\n\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content pane-highwire-permission-link\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-d5e9ecaa-460b-40c1-87fb-0dbcbc3a749d\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-d5e9ecaa-460b-40c1-87fb-0dbcbc3a749d\u0022 data-pid=\u0022new-d5e9ecaa-460b-40c1-87fb-0dbcbc3a749d\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-copyright\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ECopyright information\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022field field-name-field-highwire-copyright field-type-text field-label-hidden\u0022\u003E\u003Cdiv class=\u0022field-items\u0022\u003E\u003Cdiv class=\u0022field-item even\u0022\u003E\u003Cspan class=\u0022nlm-copyright-statement\u0022 data-hwp-id=\u0022copyright-statement-1\u0022\u003E\u0026Acirc;\u0026copy; Author(s) (or their employer(s)) 2023. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.\u003C\/span\u003E \u003Cspan class=\u0022nlm-license\u0022 data-license-type=\u0022open-access\u0022 data-xlink-href=\u0022http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/\u0022 data-hwp-id=\u0022license-1\u0022\u003E\u003Cspan class=\u0022ali-license_ref\u0022 data-start_date=\u00222023-10-21\u0022\u003E\u003Ca href=\u0022http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/\u0022\u003Ehttp:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/\u003C\/a\u003E\u003C\/span\u003E\u003Cspan class=\u0022nlm-p\u0022 data-hwp-id=\u0022p-1\u0022\u003EThis is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See \u003Ca class=\u0022nlm-ext-link\u0022 data-l-rel=\u0022related\u0022 data-l-ref-type=\u0022uri\u0022 data-l-ref=\u0022http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/\u0022 data-ext-link-type=\u0022uri\u0022 data-xlink-href=\u0022http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/\u0022 data-hwp-id=\u0022ext-link-1\u0022 href=\u0022http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/\u0022\u003Ehttp:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/\u003C\/a\u003E.\u003C\/span\u003E\u003C\/span\u003E\u003C\/div\u003E\u003C\/div\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n\t\t\t\u003C\/div\u003E\n\t\t\u003C\/div\u003E\n\t\n\t\u003C\/div\u003E \u003C!-- \/.panel-row-wrapper --\u003E\t\n\t\n\t\u003C\/div\u003E\n\n\u003C\/div\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022\/\/crossmark-cdn.crossref.org\/widget\/v2.0\/widget.js\u0022\u003E\u003C\/script\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}