{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_emoFzfXbbTdflMmmME0VF2KnfND30HvkST4A1XKeKus.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-d5e9ecaa-460b-40c1-87fb-0dbcbc3a749d\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022Del5UjD8DL1UmFwOtd3w2CgB2aWA1UX5vR\\\\\\\\\\\\\\\/LC3eQwT+FxGztwPFVram+9kcOLW7IInC8OH16KNZVdl2eSAQYzLC7QII54ehevjH1xMLMk80qwkJhNnGfjH2rdXvgI\\\\\\\\\\\\\\\/N+90+V1N1+mcP1WrwxdJRkfvChA\\\\\\\\\\\\\\\/7aOVtFAijOJekBHH6El\\\\\\\\\\\\\\\/Cx\\\\\\\\\\\\\\\/da\\\\\\\\\\\\\\\/ObxgOfc+Q2micHsY3qhHtuy8xSZ\\\\\\\\\\\\\\\/JMFkKV\\\\\\\\\\\\\\\/NxeiHsIDKSAjjva\\\\\\\\\\\\\\\/nqc2MNTEwkyngsshq8gQ6tl6lurDAHIZ7X3IbLv7BwaDv9KxU5VXT1j35bqbGi8topiTOFlPiyc0MqsN6NAnk2U\\\\\\\\\\\\\\\/okvxd3rtIalGFYIv5L\\\\\\\\\\\\\\\/RHHBKHCov4IKbTKA4B9gRRrAVY37DamGuVhrEuVAku9hOQ+wMsbk8gwkt9cN1OSFId\\\\\\\\\\\\\\\/KuujnCK1UsvDXdVvmHZnTBk\\\\\\\\\\\\\\\/DFZMponZS8+QfPebtVH0\\\\\\\\\\\\\\\/cGHi2wvfmC\\\\\\\\\\\\\\\/2z8DjN8K9+nyUvB48nQEbH0hWBv8hBtkTLwyJVZLtolVKsP9NOmnZz3oxf9ooYMgWo7wy860OiPPHqlcvBubaYm62J2RWqSaBdEnYiOYoJWhpvXkcKlMT0ZEJkDDLx+0\\\\\\\\\\\\\\\/67P3XmBUkJz\\\\\\\\\\\\\\\/mc2Njf8fndWTWTurH4XITHLFAMXUSm3xNcEyWCQG7SMvX32PeEu7TabUqF4ztFig6ObYnj5f3Q3816BZ5SuNRnvbqpXgRqqIRdsNNS1UT82M9wHb0D+qgHZwJawwaa0maqqVaZEN0RqaIfFlSxSjzFJs4nl7tiyaF95bEwCGWpbYTuWzL70xeG\\\\\\\\\\\\\\\/TulAHblHzVhK2LhfqXOPCXpf1flNh8mP0nMcr1dfQhmzlpiL7Nqwuo2iO1JJOdJJSUcMKTYEJ8tM\\\\\\\\\\\\\\\/ExSd2OzcqhNOOpevjZzItOPZH6o+GYg8hhEsTeA7O8fhE7VWFthxmCesC6coFWAHXwEcu5Q\\\\\\\\\\\\\\\/KapGqtTM5NJVhjVOoxc4mJMQGr6500m6hjcxFpFQMj2PQrxASq7ewnuysmQP3FfymaiDekpZlhLX2q1RdFlkaFvFz4jCAim0DD2f29dicRuxSGk4Oq+BahMQR0P1\\\\\\\\\\\\\\\/z6F8W0CHo9xhMPMSyFQyMpvT3JUtwg+V9olv4YQmsQBOqlqQ8j7QSsNEm+KzUu4sJLcVKlf5wFbajfRd7183TsCi3Jv6wZ70yCM9dRDRsEYnPJWot7ud3hqKOGITFsKz8Xhh881kfHBSOAcuXSjCAfZYK5c\\\\\\\\\\\\\\\/2CfkdABHeiKbQulhyjRodNpO5GBaJONaCjr+QvKrvo\\\\\\\\\\\\\\\/bMDqmnc0RCkg5zeBJgiuLjs+H+zgWxKTP5YofDbsbAamtsN\\\\\\\\\\\\\\\/S8MgFj\\\\\\\\\\\\\\\/Yn3xisiA38tQlRZCGTKsz6mnQbsl2bkJTPWirCRAwi+6jtAlXzcKbuyxuyjasoQT9ZBBXR37gUVVJZGzjapo1zNouy8HNLKCeodBBEJaLiuutHwexsABOypR9QctLAYt1Bph3fJl7Qsp9v5h4QexMoLYId0wBjB2lJAUAV7xgLJ\\\\\\\\\\\\\\\/rcRRA0m9YSm5Gtj2HS3tePzJQUqj4J3bN2NRF8PZcLAt\\\\\\\\\\\\\\\/35IE0ErpGGDnxlcTbGHoN+es06OlHUs1b+JoPDKSuoI0wD51\\\\\\\\\\\\\\\/3pS9JlPMqUXQlvnqJdu923ts25VTQKdl9hGlOq\\\\\\\\\\\\\\\/hiVoiqOtR5aC3Rw6I5DJyDvqb7q31Z+9t5VQibMzRif3z5eyrWlopxwxRU9jn3+vIaJRCaHjY9FJl7JSSwl85VuWa60z0rVrmaaVPGbQwORaHblJ6ekRFrmd3oNf3eC9hop4JRq1cE6jqQ42bvuAIC0MSdnHmPTpCpFhuMzIvH7VdZivW+pivWKOqK5pRLP7\\\\\\\\\\\\\\\/rvjk5OosXEQI6ZL+Zo9hE8FW07BMmSANcedGXgOQKo6Zm9VkKriV\\\\\\\\\\\\\\\/u5iLTM4V3AzmNmjL6SbL\\\\\\\\\\\\\\\/0NSttTxRJ\\\\\\\\\\\\\\\/9SWipfCACPhkeG9zofjWpLYACcukdHaf24CoBY180ebOVEDX56nOdS2iEe239ClZNIflQvxURqLJKZYSKXQDmD\\\\\\\\\\\\\\\/6kX3mhC4i6WBI2vlru6BQv0cqQNLQ7h4vkDcyDUAtV++OpFLZzH1Z2PMdDo\\\\\\\\\\\\\\\/XHH15RKCrjfyGYtRczDZtF40ORf37FFBcSyH+nc0MGzSNzga6ZfWf7hjudFH5fx3C0kNigPK63nerl+aDZwQPeao54GEB6MYN5OqJ5ho6tC5lv2i+GGqOiA9gRCElQQe4CySIG\\\\\\\\\\\\\\\/iUMXQE05ZDHXrUfRMgxMdqPrvYJ2k0tKSgdqncYs0jOam7k2hgyVYBlPWnOPJyKb212IIncxH1pc61+\\\\\\\\\\\\\\\/bcDHui3chvUL9fK277PGqlvFqB\\\\\\\\\\\\\\\/ABXQqABfop2xT\\\\\\\\\\\\\\\/5c5fe\\\\\\\\\\\\\\\/HTUIPl3JNo8vzcvLeON3Y4PFww2zKxaQ5pglUXwKzXLju29X0knNG3GNmysTaooB0fSqithPihxPnLKKeqa2BKZfY8QCNXKCGSIFr5znoasaKXl3pUJ+Bi8DwXHOk7jRm+WvCxhjMcENhAbE7F5Uf1mibSThHy0oJ98zK9kmrkgnghVWeA7WT47kU940izy27vHexMmVzEOjnNbqy5EhuDeS6NwbX3Z1JeQTLu1udOZNLK1i7JQ5lmphZLR4udAKm1obTNYoNFbOz87crmTny\\\\\\\\\\\\\\\/5F3BLy9IRyRVHwJoqXF8npxWwvq+I7P6\\\\\\\\\\\\\\\/nQMv8RWEHTzGWCZ1rTLJFTdTcq+WLTIhKHG8m0J08TNy09hsr1ZgZHok6N7zc7rupAC+CR46xd55aCPwBNZbbOBPlRjAS8uMSFEMdVZhsvuvlz5t6ex3oxPGYn5jzVZMpXC4F7N0YhxSZ5Svh07ILGabaFiYq2cGqnhrgq4rW3htPcJMdRNgXg7NtHqqZWd8feTKaH+Tvp0HrXWiY5FTbFNPTyhY5WAanElkggXW3uQE6BU3S+NQcoah1knpobGwXXbUBUtphZAcoru72xOezZexKxK8OOg==\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022ZXbrmMrKKG+dUXA9lRy4YA==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u00225a3b76173fcb67c50e97cde593f0a79a87879a5f585838efe8d258e8232866ff\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/3\\\/1\\\/30.atom\u0022:{\u0022access\u0022:{\u0022full\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/3\\\/1\\\/30.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022bmjj\u0022:{\u0022show_corresp\u0022:false},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u0022sites\\\/default\\\/modules\\\/jnl_template_bmjj\\\/plugins\\\/content_types\\\/js\\\/bmjj-contributors.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__XqNETqO2KISUuux0IjZeixOTFnSk20iJyWcdyjFvJv0__V5XKdmT7SKbPMZ3oiYeZn3IKAzRNs6WzDcLxN472J6o__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-art-info\u0022\u003E\u003Cdiv class=\u0022panel-display highwire-1col-stacked-layout\u0022\u003E\n\t  \u003Cdiv class=\u0022panel-row-wrapper panel-row-first clearfix\u0022\u003E\n\t\t\n\t\t\u003Cdiv class=\u0022top-wrapper\u0022\u003E\n\t\t\t\u003Cdiv class=\u0022panel-panel panel-region-top\u0022\u003E\n\t\t\t  \u003Cdiv class=\u0022inside\u0022\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-article-crossmark\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003C!-- Start CrossMark Snippet v2.0 --\u003E\n    \u003Ca data-target=\u0022crossmark\u0022 class=\u0022crossmark-square\u0022\u003E\u003Cimg src=\u0022https:\/\/crossmark-cdn.crossref.org\/widget\/v2.0\/logos\/CROSSMARK_Color_square.svg\u0022 alt=\u0022\u0022\u003E\u003C\/a\u003E\n    \u003Cdiv id=\u0022crossmark-dialog\u0022 style=\u0022display: none;\u0022 title=\u0022\u0022\u003E\n    \u003C!-- the external CrossMark data is loaded inside this iframe --\u003E\n    \u003Ciframe id=\u0022crossmark-dialog-frame\u0022\u003E\u003C\/iframe\u003E\n    \u003C\/div\u003E\n    \u003C!-- End CrossMark Snippet --\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-bmjj-contributors author-ids col-narrow-12\u0022\u003E\n  \n        \u003Ch3 class=\u0022pane-title\u0022\u003EAuthors\u003C\/h3\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022field field-name-field-highwire-a-contributors field-type-text field-label-hidden\u0022\u003E\u003Cdiv class=\u0022field-items\u0022\u003E\u003Cdiv class=\u0022field-item even\u0022\u003E\u003Cdiv class=\u0022highwire-list-wrapper\u0022\u003E\u003Cdiv class=\u0022highwire-list\u0022\u003E\u003Cul class=\u0022highwire-contributors-list single-contrib\u0022\u003E\u003Cli class=\u0022first last odd\u0022\u003E\u003Cspan class=\u0022nlm-given-names\u0022\u003ESylvia\u003C\/span\u003E \u003Cspan class=\u0022nlm-surname\u0022\u003EJanetzki\u003C\/span\u003E \u003Cspan class=\u0022nlm-aff\u0022\u003E\n\n\u003Cspan class=\u0022nlm-institution-wrap\u0022\u003E\u003Cspan class=\u0022nlm-institution\u0022 data-content-type=\u0022org-name\u0022 data-hwp-id=\u0022institution-1\u0022\u003EZellNet Consulting, Inc.\u003C\/span\u003E\u003C\/span\u003E\n\u003Cspan class=\u0022nlm-addr-line\u0022 data-content-type=\u0022street\u0022\u003E555 North Avenue, Ste. 25-S\u003C\/span\u003E\n\u003Cspan class=\u0022nlm-addr-line\u0022 data-content-type=\u0022postcode\u0022\u003E07024\u003C\/span\u003E\n\u003Cspan class=\u0022nlm-addr-line\u0022 data-content-type=\u0022city\u0022\u003EFort Lee\u003C\/span\u003E\n\u003Cspan class=\u0022nlm-addr-line\u0022 data-content-type=\u0022state\u0022\u003ENJ\u003C\/span\u003E\n\u003Cspan class=\u0022nlm-country\u0022 data-country=\u0022US\u0022\u003EUSA\u003C\/span\u003E\n\u003C\/span\u003E \u003Ca href=\u0022\/lookup\/external-ref?access_num=Janetzki%20S\u0026amp;link_type=AUTHORSEARCH\u0022 target=\u0022_blank\u0022 class=\u0022authour-link\u0022 data-icon-position=\u0022\u0022 data-hide-link-title=\u00220\u0022\u003EPubMed articles\u003C\/a\u003E\u003Ca href=\u0022\/lookup\/google-scholar?author%5B0%5D=%22author%3ASylvia%20Janetzki%22\u0026amp;gs_type=author\u0022 target=\u0022_blank\u0022 class=\u0022authour-link\u0022 data-icon-position=\u0022\u0022 data-hide-link-title=\u00220\u0022\u003EGoogle scholar articles\u003C\/a\u003E\u003C\/li\u003E\u003C\/ul\u003E\u003C\/div\u003E\u003C\/div\u003E\u003C\/div\u003E\u003C\/div\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n\t\t\t\u003C\/div\u003E\n\t\t\u003C\/div\u003E\n\t\n\t\u003C\/div\u003E \u003C!-- \/.panel-row-wrapper --\u003E\t\n\t  \n  \u003Cdiv class=\u0022panel-row-wrapper clearfix\u0022\u003E\n\t\t\n\t\t\u003Cdiv class=\u0022content-wrapper\u0022\u003E\n\t\t\t\u003Cdiv class=\u0022panel-panel panel-region-content\u0022\u003E\n\t\t\t  \u003Cdiv class=\u0022inside\u0022\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-article-citation\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ECitation\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022highwire-article-citation highwire-citation-type-highwire-article node4132\u0022 data-node-nid=\u00224132\u0022 id=\u0022node-4132--21209180968\u0022 data-pisa=\u0022jitc;3\/1\/30\u0022 data-pisa-master=\u0022jitc;10.1186\/s40425-015-0074-0\u0022 data-apath=\u0022\/jitc\/3\/1\/30.atom\u0022\u003E\u003Cdiv class=\u0022highwire-cite highwire-cite-highwire-article highwire-citation-v1-cp clearfix bmjj-article-citation\u0022\u003E\n  \n  \n    \t\u003Cdiv class=\u0022highwire-cite-authors\u0022\u003E\u003Cspan class=\u0022highwire-citation-authors\u0022\u003E\u003Cspan class=\u0022highwire-citation-author first\u0022 data-delta=\u00220\u0022\u003E\u003Cspan class=\u0022nlm-surname\u0022\u003EJanetzki\u003C\/span\u003E S\u003C\/span\u003E\u003C\/span\u003E\u003C\/div\u003E\n  \n      \u003Cdiv class=\u0022highwire-cite-title\u0022\u003EImmune monitoring technology primer: the enzyme-linked immunospot (Elispot) and Fluorospot assay\u003C\/div\u003E  \n      \n    \t\u003Cdiv class=\u0022highwire-cite-metadata bmjj-citation-metadata\u0022\u003E\u003Cspan class=\u0022highwire-cite-metadata-journal highwire-cite-metadata\u0022\u003EJournal for ImmunoTherapy of Cancer \u003C\/span\u003E\u003Cspan class=\u0022highwire-cite-metadata-year highwire-cite-metadata\u0022\u003E2015;\u003C\/span\u003E\u003Cspan class=\u0022highwire-cite-metadata-volume highwire-cite-metadata\u0022\u003E3:\u003C\/span\u003E\u003Cspan class=\u0022highwire-cite-metadata-elocation-id highwire-cite-metadata\u0022\u003E30. \u003C\/span\u003E\u003Cspan class=\u0022highwire-cite-metadata-doi highwire-cite-metadata\u0022\u003E\u003Cspan class=\u0022label\u0022\u003Edoi:\u003C\/span\u003E 10.1186\/s40425-015-0074-0 \u003C\/span\u003E\u003C\/div\u003E\n  \n  \n  \n\u003C\/div\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-mini pane-jnl-template-bmjj-art-pub-history\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panel-display highwire-1col-stacked-layout\u0022 id=\u0022mini-panel-jnl_template_bmjj_art_pub_history\u0022\u003E\n\t  \n  \u003Cdiv class=\u0022panel-row-wrapper clearfix\u0022\u003E\n\t\t\n\t\t\u003Cdiv class=\u0022content-wrapper\u0022\u003E\n\t\t\t\u003Cdiv class=\u0022panel-panel panel-region-content\u0022\u003E\n\t\t\t  \u003Cdiv class=\u0022inside\u0022\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-pubdate bmjj-pub-date\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022field field-name-field-highwire-a-epubdate field-type-datetime field-label-inline clearfix\u0022\u003E\u003Cdiv class=\u0022field-label\u0022\u003EOnline issue publication\u0026nbsp;\u003C\/div\u003E\u003Cdiv class=\u0022field-items\u0022\u003E\u003Cdiv class=\u0022field-item even\u0022\u003E\u003Cspan class=\u0022date-display-single\u0022\u003EFebruary 16, 2021\u003C\/span\u003E\u003C\/div\u003E\u003C\/div\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n\t\t\t\u003C\/div\u003E\n\t\t\u003C\/div\u003E\n\t\n\t\u003C\/div\u003E \u003C!-- \/.panel-row-wrapper --\u003E\t\n\t\n\t\u003C\/div\u003E\n\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content pane-highwire-permission-link\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-d5e9ecaa-460b-40c1-87fb-0dbcbc3a749d\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-d5e9ecaa-460b-40c1-87fb-0dbcbc3a749d\u0022 data-pid=\u0022new-d5e9ecaa-460b-40c1-87fb-0dbcbc3a749d\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-copyright\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ECopyright information\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022field field-name-field-highwire-copyright field-type-text field-label-hidden\u0022\u003E\u003Cdiv class=\u0022field-items\u0022\u003E\u003Cdiv class=\u0022field-item even\u0022\u003E\u003Cspan class=\u0022nlm-copyright-statement\u0022 data-hwp-id=\u0022copyright-statement-1\u0022\u003E\u0026Atilde;\u0026#130;\u0026Acirc;\u0026copy; The Author(s). 2015\u003C\/span\u003E \u003Cspan class=\u0022nlm-license\u0022 data-license-type=\u0022open-access\u0022 data-xlink-href=\u0022http:\/\/creativecommons.org\/licenses\/\u0022 data-hwp-id=\u0022license-1\u0022\u003E\u003Cspan class=\u0022nlm-p\u0022 data-hwp-id=\u0022p-2\u0022\u003EThis is an Open Access article distributed under the terms of the Creative Commons Attribution License (\u003Ca class=\u0022nlm-ext-link\u0022 data-l-rel=\u0022related\u0022 data-l-ref-type=\u0022uri\u0022 data-l-ref=\u0022http:\/\/creativecommons.org\/licenses\/by\/2.0\u0022 data-ext-link-type=\u0022uri\u0022 data-xlink-href=\u0022http:\/\/creativecommons.org\/licenses\/by\/2.0\u0022 data-hwp-id=\u0022ext-link-1\u0022 href=\u0022http:\/\/creativecommons.org\/licenses\/by\/2.0\u0022\u003Ehttp:\/\/creativecommons.org\/licenses\/by\/2.0\u003C\/a\u003E), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited.\u003C\/span\u003E\u003C\/span\u003E\u003C\/div\u003E\u003C\/div\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n\t\t\t\u003C\/div\u003E\n\t\t\u003C\/div\u003E\n\t\n\t\u003C\/div\u003E \u003C!-- \/.panel-row-wrapper --\u003E\t\n\t\n\t\u003C\/div\u003E\n\n\u003C\/div\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022\/\/crossmark-cdn.crossref.org\/widget\/v2.0\/widget.js\u0022\u003E\u003C\/script\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}