Immunomodulation

IL-6 contributes to metastatic switch via the differentiation of monocytic-dendritic progenitors into prometastatic immune cells
Ksenia Magidey-Klein, Tim J Cooper, Ksenya Kveler, Rachelly Normand, Tongwu Zhang, Michael Timaner, Ziv Raviv, Brian P. James, Roi Gazit, Ze'ev A. Ronai, Shai Shen-Orr, Yuval Shaked

Journal for ImmunoTherapy of Cancer Jun 2021, 9 (6) e002856; DOI: 10.1136/jitc-2021-002856
Cancer environmental immunotherapy: starving tumor cell to death by targeting TGFB on immune cell
Xing Huang, Gang Zhang, Tingbo Liang

Journal for ImmunoTherapy of Cancer Jun 2021, 9 (6) e002823; DOI: 10.1136/jitc-2021-002823
S100A4 enhances protumor macrophage polarization by control of PPAR-γ-dependent induction of fatty acid oxidation
Shuangqing Liu, Huilei Zhang, Yanan Li, Yana Zhang, Yangyang Bian, Yanqiong Zeng, Xiaohan Yao, Jiajia Wan, Xu Chen, Jianru Li, Zhaoqing Wang, Zhihai Qin

Journal for ImmunoTherapy of Cancer Jun 2021, 9 (6) e002548; DOI: 10.1136/jitc-2021-002548
Off-tumor IDO1 target engagements determine the cancer-immune set point and predict the immunotherapeutic efficacy
Lin Xie, Kuan Hu, Yanhong Duo, Takashi Shimokawa, Katsushi Kumata, Yiding Zhang, Cuiping Jiang, Lulu Zhang, Nobuki Nengaki, Hidekatsu Wakizaka, Yihai Cao, Ming-Rong Zhang

Journal for ImmunoTherapy of Cancer Jun 2021, 9 (6) e002616; DOI: 10.1136/jitc-2021-002616
Circulating myeloid-derived suppressor cells and regulatory T cells as immunological biomarkers in refractory/relapsed diffuse large B-cell lymphoma: translational results from the R2-GDP-GOTEL trial
Carlos Jiménez-Cortegana, Natalia Palazón-Carrión, Alejandro Martin Garcia-Sancho, Esteban Nogales-Fernandez, Fernando Carnicero-González, Eduardo Ríos-Herranz, Fatima de la Cruz-Vicente, Guillermo Rodríguez-García, Rubén Fernández-Álvarez, Antonio Rueda Dominguez, Maria Casanova-Espinosa, Natividad Martínez-Banaclocha, Josep Gumà-Padrò, José Gómez-Codina, Jorge Labrador, Antonio Salar-Silvestre, Delvys Rodriguez-Abreu, Laura Galvez-Carvajal, Mariano Provencio, Margarita Sánchez-Beato, María Guirado-Risueño, Pablo Espejo-García, Marylene Lejeune, Tomás Álvaro, Victor Sánchez-Margalet, Luis de la Cruz-Merino

Journal for ImmunoTherapy of Cancer Jun 2021, 9 (6) e002323; DOI: 10.1136/jitc-2020-002323
Neoadjuvant chemoradiation alters biomarkers of anticancer immunotherapy responses in locally advanced rectal cancer
Incheol Seo, Hye Won Lee, Sang Jun Byun, Jee Young Park, Hyeonji Min, Sung Hwan Lee, Ju-Seog Lee, Shin Kim, Sung Uk Bae

Journal for ImmunoTherapy of Cancer Mar 2021, 9 (3) e001610; DOI: 10.1136/jitc-2020-001610
Host response to immune checkpoint inhibitors contributes to tumor aggressiveness
Irina Khononov, Eyal Jacob, Ella Fremder, Nili Dahan, Michal Harel, Ziv Raviv, Boris Krastev, Yuval Shaked

Journal for ImmunoTherapy of Cancer Mar 2021, 9 (3) e001996; DOI: 10.1136/jitc-2020-001996
Regorafenib enhances antitumor immunity via inhibition of p38 kinase/Creb1/Klf4 axis in tumor-associated macrophages
Da-Liang Ou, Chia-Wei Chen, Chia-Lang Hsu, Chih-Hung Chung, Zi-Rui Feng, Bin-Shyun Lee, Ann-Lii Cheng, Muh-Hwa Yang, Chiun Hsu

Journal for ImmunoTherapy of Cancer Mar 2021, 9 (3) e001657; DOI: 10.1136/jitc-2020-001657
Progesterone promotes immunomodulation and tumor development in the murine mammary gland
Lauryn R Werner, Katelin A Gibson, Merit L Goodman, Dominika E Helm, Katherine R Walter, Sean M Holloran, Gloria M Trinca, Richard C Hastings, Howard H Yang, Ying Hu, Junping Wei, Gangjun Lei, Xiao-Yi Yang, Rashna Madan, Alfredo A Molinolo, Mary A Markiewicz, Prabhakar Chalise, Margaret L Axelrod, Justin M Balko, Kent W Hunter, Zachary C Hartman, Carol A Lange, Christy R Hagan

Journal for ImmunoTherapy of Cancer May 2021, 9 (5) e001710; DOI: 10.1136/jitc-2020-001710
DNGR-1 limits Flt3L-mediated antitumor immunity by restraining tumor-infiltrating type I conventional dendritic cells
Francisco J Cueto, Carlos del Fresno, Paola Brandi, Alexis J. Combes, Elena Hernández-García, Alfonso R Sánchez-Paulete, Michel Enamorado, Christian P Bromley, Manuel J Gomez, Ruth Conde-Garrosa, Santos Mañes, Santiago Zelenay, Ignacio Melero, Salvador Iborra, Matthew F. Krummel, David Sancho

Journal for ImmunoTherapy of Cancer May 2021, 9 (5) e002054; DOI: 10.1136/jitc-2020-002054

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