breast neoplasms

Combination of a novel heat shock protein 90-targeted photodynamic therapy with PD-1/PD-L1 blockade induces potent systemic antitumor efficacy and abscopal effect against breast cancers
Kensuke Kaneko, Chaitanya R Acharya, Hiroshi Nagata, Xiao Yang, Zachary Conrad Hartman, Amy Hobeika, Philip F Hughes, Timothy A J Haystead, Michael A Morse, Herbert Kim Lyerly, Takuya Osada

Journal for ImmunoTherapy of Cancer Sep 2022, 10 (9) e004793; DOI: 10.1136/jitc-2022-004793
Restoration of p53 activity via intracellular protein delivery sensitizes triple negative breast cancer to anti-PD-1 immunotherapy
Zaofeng Yang, Jacquelyne Ka-Li Sun, Marianne M Lee, Michael K Chan

Journal for ImmunoTherapy of Cancer Sep 2022, 10 (9) e005068; DOI: 10.1136/jitc-2022-005068
Elicitation of stem-like CD8⁺ T cell responses via lymph node-targeted chemoimmunotherapy evokes systemic tumor control
Margaret P Manspeaker, Meghan J O'Melia, Susan N Thomas

Journal for ImmunoTherapy of Cancer Sep 2022, 10 (9) e005079; DOI: 10.1136/jitc-2022-005079
Ccl3 enhances docetaxel chemosensitivity in breast cancer by triggering proinflammatory macrophage polarization
Dandan Sheng, Wei Ma, Rui Zhang, Lei Zhou, Qiaodan Deng, Juchuanli Tu, Weilong Chen, Fuchuang Zhang, Nailong Gao, Mengxue Dong, Dong Wang, Fengkai Li, Yin Liu, Xueyan He, Shengzhong Duan, Lixing Zhang, Tong Liu, Suling Liu

Journal for ImmunoTherapy of Cancer May 2022, 10 (5) e003793; DOI: 10.1136/jitc-2021-003793
Evaluation of tumor immune contexture among intrinsic molecular subtypes helps to predict outcome in early breast cancer
Quentin Klopfenstein, Valentin Derangère, Laurent Arnould, Marion Thibaudin, Emeric Limagne, Francois Ghiringhelli, Caroline Truntzer, Sylvain Ladoire

Journal for ImmunoTherapy of Cancer Jun 2021, 9 (6) e002036; DOI: 10.1136/jitc-2020-002036
Phase II clinical trial using anti-CD3 × anti-HER2 bispecific antibody armed activated T cells (HER2 BATs) consolidation therapy for HER2 negative (0–2+) metastatic breast cancer
Lawrence G. Lum, Zaid Al-Kadhimi, Abhinav Deol, Vidya Kondadasula, Dana Schalk, Elyse Tomashewski, Patricia Steele, Kristie Fields, Melissa Giroux, Qin Liu, Lawrence Flaherty, Michael Simon, Archana Thakur

Journal for ImmunoTherapy of Cancer Jun 2021, 9 (6) e002194; DOI: 10.1136/jitc-2020-002194
IGF1 receptor inhibition amplifies the effects of cancer drugs by autophagy and immune-dependent mechanisms
Qi Wu, Ai-Ling Tian, Bei Li, Marion Leduc, Sabrina Forveille, Peter Hamley, Warren Galloway, Wei Xie, Peng Liu, Liwei Zhao, Shuai Zhang, Pan Hui, Frank Madeo, Yi Tu, Oliver Kepp, Guido Kroemer

Journal for ImmunoTherapy of Cancer Jun 2021, 9 (6) e002722; DOI: 10.1136/jitc-2021-002722
Identification and validation of expressed HLA-binding breast cancer neoepitopes for potential use in individualized cancer therapy
Hannah Reimann, Andrew Nguyen, J Zachary Sanborn, Charles J Vaske, Stephen C Benz, Kayvan Niazi, Shahrooz Rabizadeh, Patricia Spilman, Andreas Mackensen, Matthias Ruebner, Alexander Hein, Matthias W Beckmann, Edith D van der Meijden, Judith Bausenwein, Sascha Kretschmann, Marieke Griffioen, Jeffrey Schlom, James L Gulley, Karin L Lee, Duane H Hamilton, Patrick Soon-Shiong, Peter A Fasching, Anita N. Kremer

Journal for ImmunoTherapy of Cancer Jun 2021, 9 (6) e002605; DOI: 10.1136/jitc-2021-002605
Extracellular HMGB1 blockade inhibits tumor growth through profoundly remodeling immune microenvironment and enhances checkpoint inhibitor-based immunotherapy
Pascale Hubert, Patrick Roncarati, Stephanie Demoulin, Charlotte Pilard, Marie Ancion, Celia Reynders, Thomas Lerho, Diane Bruyere, Alizee Lebeau, Coraline Radermecker, Margot Meunier, Marie-Julie Nokin, Elodie Hendrick, Olivier Peulen, Philippe Delvenne, Michael Herfs

Journal for ImmunoTherapy of Cancer Mar 2021, 9 (3) e001966; DOI: 10.1136/jitc-2020-001966
Pre-existing effector T-cell levels and augmented myeloid cell composition denote response to CDK4/6 inhibitor palbociclib and pembrolizumab in hormone receptor-positive metastatic breast cancer
Colt Egelston, Weihua Guo, Susan Yost, Jin Sun Lee, David Rose, Christian Avalos, Jian Ye, Paul Frankel, Daniel Schmolze, James Waisman, Peter Lee, Yuan Yuan

Journal for ImmunoTherapy of Cancer Mar 2021, 9 (3) e002084; DOI: 10.1136/jitc-2020-002084

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