Table 4:

Diagnostic performance of DCE-MR imaging parameters for each tumor comparisona

ParametersChondrosarcoma vs ChordomaChondrosarcoma vs MetastasisChordoma vs Metastasis
nADCmeanVpnADCmeanVpKtrans (minute−1)VpKtrans (minute−1)
Cutoff1.990.032.090.060.120.090.30
Sensitivity1.0 (0.68–1)0.93 (0.66–0.99)0.93 (0.76–0.99)0.93 (0.78–0.99)0.93 (0.78–0.99)0.80 (0.61–0.92)0.60 (0.41–0.77)
Specificity0.86 (0.57–0.98)0.71 (0.42–0.92)0.87 (0.60–0.98)0.93 (0.66–0.9)0.71 (0.42–0.92)0.93 (0.66–1)1.0 (0.68–1)
PPV0.88 (0.62–0.98)0.77 (0.50–0.93)0.93 (0.76–0.99)0.97 (0.82–1)0.88 (0.71–0.97)0.96 (0.80–1)1.0 (0.74–1)
NPV1.0 (0.64–1)0.91 (0.59–0.99)0.87 (0.60–0.98)0.87 (0.60–0.98)0.83 (0.52–0.98)0.68 (0.43–0.87)0.54 (0.33–0.73)
Accuracy0.93 (0.78–0.99)0.82 (0.63–0.94)0.91 (0.77–0.97)0.93 (0.81–0.99)0.86 (0.73–0.95)0.84 (0.70–0.93)0.73 (0.57–0.85)
AUC0.96 (0.90–1)0.86 (0.72–1)0.95 (0.88–1)0.99 (0.96–1)0.82 (0.67–0.98)0.92 (0.84– 1)0.82 (0.70–0.95)
  • Note:—PPV indicates positive predictive value; NPV, negative predictive value.

  • a Numbers in parentheses represent 95% CIs.