Table 3:

Bivariate analysis between baseline variables and intracranial aneurysms

Baseline CharacteristicsIntracranial Aneurysm (n = 33)No Intracranial Aneurysm (n = 195)P Valuea
Sex (female) (No.) (%)21 (63.6%)120 (61.5%).85
Age (median) (IQR) (yr)51.4 (43.3–69.3)48.0 (38–63.2).10
Curaçao criteria (No.) (%)
    Epistaxis33 (100%)176 (90.3%).08
    Telangiectasias32 (97.0%)187 (95.9%)1.00
    AVMs25 (75.8%)138 (70.8%).68
    Family history26 (78.8%)171 (87.7%).17
BVMs (No.) (%)13 (39.4%)47 (24.1%).09
AVMs (No.) (%)7 (21.2%)32 (16.4%).46
Hypertension (n = 198) (No.) (%)b8 (25.8%)29 (18.0%).32
Tobacco use (n = 189) (No.) (%)b11 (33.3%)39 (25.0%).39
Extracranial aneurysms (No.) (%) (n = 140)b7 (35.0%)20 (16.7%).07
Genetic results (No.) (%) (n = 81)b9 (27.3%)72 (36.9%)
    ENG4 (44.4%)35 (48.6%)
    ACVRL13 (33.3%)22 (30.6%).43
    MADH4010 (13.9%)
    Noninformative2 (22.2%)5 (6.9%)
  • a Two-sided P values. Medians are analyzed with Mann-Whitney U tests, and dichotomous variables, with the Fisher exact test.

  • b Included patients with available data for analysis from the medical record system.