Patients with GH-secretory pituitary adenomas who did or did not achieve a normalized IGF-1 level before their most recent MR imaging
| Characteristic | Normalized IGF-1 (95% CI) (n = 9) | Elevated IGF-1 (95% CI) (n = 7) | Difference (95% CI) | P Value |
|---|---|---|---|---|
| Extraocular muscle size at most recent MR imaging (mm) | 3.9 (3.6–4.2) | 4.7 (4.3–5.0) | 0.7 (0.3–1.2) | <.001 |
| Average IGF-1/ULN at diagnosis | 1.9 (1.5–2.3) | 2.8 (2.3–3.4) | 0.9 (0.2–1.5) | .010 |
| Size of pituitary adenoma (mm) | 19.1 (15.9–22.3) | 23.9 (17.4–30.3) | 4.7 (−2.1–11.6) | .170 |
| Average duration of elevated IGF-1 (mo) | 20.4 (12.4–28.5) | 39.3 (18.8–59.9) | 18.9 (−2.3–40.1) | .078 |
| Average time between initial and final MR imaging (mo) | 52.8 (26.1–79.4) | 39.9 (19.7–60.1) | −12.9 (−45.0–19.1) | .417 |