Reader-individual diagnostic performances with/without CAD assistance
| Reader | Human without CAD Assistance | Human with CAD Assistance | Human without vs with CAD Assistance (P Value) | |
|---|---|---|---|---|
| Sensitivity (%) (95% CI) | Neurologist | 56.3 (47.9–64.7) | 84.4 (78.3–90.6) | <.001 |
| Neurosurgeon | 74.8 (67.5–82.1) | 85.2 (79.2–91.2) | .032 | |
| Radiologist | 86.7 (80.9–92.4) | 83.7 (77.5–89.9) | .493 | |
| Resident | 76.3 (69.1–83.5) | 92.6 (88.2–97) | .001 | |
| Specificity (%) (95% CI) | Neurologist | 90.9 (86.8–94.9) | 92.9 (89.3–96.5) | .460 |
| Neurosurgeon | 92.9 (89.3–96.5) | 93.4 (89.9–96.9) | .842 | |
| Radiologist | 95.9 (93.2–98.7) | 94.9 (91.9–98) | .629 | |
| Resident | 99.5 (98.5–100) | 99.5 (98.5–100) | >.999 | |
| Sensitivity per lesion (%) (95% CI) | Neurologist | 60.4 (53–67.7) | 91.7 (87.2–96.3) | <.001 |
| Neurosurgeon | 82.2 (76–88.5) | 96.4 (93.7–99.2) | <.001 | |
| Radiologist | 90.5 (85.7–95.3) | 95.3 (92.2–98.3) | .070 | |
| Resident | 80.5 (74.6–86.4) | 96.4 (93.7–99.2) | <.001 | |
| No. of false-positives per case (95% CI) | Neurologist | 0.066 (0.044–0.099) | 0.072 (0.048–0.108) | .751 |
| Neurosurgeon | 0.069 (0.047–0.103) | 0.09 (0.062–0.132) | .200 | |
| Radiologist | 0.039 (0.022–0.07) | 0.075 (0.051–0.112) | .028 | |
| Resident | 0.006 (0.002–0.024) | 0.018 (0.008–0.04) | .179 |