Association between PSMD and cognitive performance in subjects with CAA-MCI and non-CAA-MCIa
| Adjusted Modelb | |||||
|---|---|---|---|---|---|
| Std. β | 95% CI | P Value | |||
| CAA-MCI (n = 24) | |||||
| Global cognitive status | –0.40 | –1.21 | 0.41 | .31 | |
| Memory | –0.69 | –1.52 | 0.15 | .10 | |
| Processing speed/attention | –1.08 | –1.76 | –0.40 | .004c | |
| Language | –0.47 | –1.16 | 0.21 | .16 | |
| Executive function | –0.64 | –1.37 | 0.10 | .09 | |
| non-CAA-MCI (n = 62) | |||||
| Global cognitive status | 0.30 | –0.13 | 0.72 | .17 | |
| Memory | 0.14 | –0.28 | 0.56 | .50 | |
| Processing speed/attention | 0.16 | –0.27 | 0.59 | .46 | |
| Language | 0.14 | –0.29 | 0.57 | .52 | |
| Executive function | 0.11 | –0.30 | 0.53 | .58 | |
↵a Multiple regression models with cognitive performance as the dependent variable.
↵b Models include PSMD, nWMHV, nTBV, CSO-PVS score, the presence of cSS and lobar CMB count; adjusting for the time delay between the neuropsychological evaluation and the MRI. In subjects with non-CAA-MCI, the presence of cSS and the lobar CMB count were automatically excluded from the models due to an absence of variance within the group.
↵c Significant.