Table 1:

Different origin of the MMA with modifications associated and embryologic explanation

Variations in the Origin of the MMAEmbryologic Implications
TypeAssociated ChangesEmbryologic ExplanationEmbryo Size (mm)
IMA originNormal anatomyNormal embryology
Basilar artery originAbsence foramen spinosumAnastomosis between SA and trigeminal artery; anastomosis between SA and lateral pontine artery12
Cavernous ICA originAbsence foramen spinosumAnastomosis between inferolateral trunk and SA16
Partial persistent SAAbsence foramen spinosum; enlargement of the facial canalRegression of the proximal part of the maxillomandibular branch; persistence of the intratympanic segment of the SA24
Complete persistent SAEnlargement of the facial canalLack of annexation of the maxillomandibular branch by the ventral pharyngeal artery; persistence of the intratympanic segment of the SA24
Pseudopetrous ICA originAbsence foramen spinosum; enlargement of the facial canal; absence of the exocranial opening of the carotid canalAgenesis of the first and second segments of the ICA; intratympanic anastomosis between inferior tympanic and caroticotympanic arteries; persistence of the intratympanic segment of the SA4–5; 24
Cervical ICA originAbsence foramen spinosum; enlargement of the facial canalIntratympanic anastomosis between inferior and superior tympanic arteries; regression of the proximal part of the maxillomandibular branch; persistence of the intratympanic segment of the SA16; 24
Occipital artery originAbsence foramen spinosum; enlargement of the facial canalNo clear explanation
Distal petrous ICA originAbsence foramen spinosumLack of annexation of the mandibular artery (first aortic arch) by the SA (second aortic arch)9