Predictive performance of clinical and image-based featuresa
| Positive Pathology | Positive Pathology and/or Microbiology | |||||
|---|---|---|---|---|---|---|
| AUC | Sensitivity | Specificity | AUC | Sensitivity | Specificity | |
| CRP, ESR, and fever | 0.72 | 68.2 | 67.0 | 0.68 | 60.5 | 64.5 |
| CRP, ESR, fever, and epidural enhancement (observer 1) | 0.87 | 83.1 | 79.8 | 0.76 | 68.4 | 75.6 |
| CRP, ESR, fever, and epidural enhancement (observer 2) | 0.76 | 75.0 | 66.5 | 0.73 | 59.6 | 76.2 |
| CRP, ESR, fever, and epidural enhancement (observer 3) | 0.79 | 77.2 | 70.1 | 0.78 | 69.3 | 75.8 |
| CRP, ESR, fever, and epidural enhancement (majority consensus) | 0.80 | 78.3 | 75.6 | 0.79 | 77.4 | 74.6 |
↵a Logistic regression with backward stepwise selection was used to find the optimal combination of clinical and imaging features for 3 independent observers with majority consensus among the observers.