Comparison of automated TBV and TIV estimates with manual ground truth estimatesa
| Parameter/Method | %Difference | Pearson’s r (P Value) | ICC (P Value) | Bootstrap Mean ICC (95% CI) |
|---|---|---|---|---|
| TBV | ||||
| CTSeg probabilistic | –7.22±2.98 | 0.96 (<.001) | 0.74 (<.001) | 0.727 (0.724–0.730) |
| CTSeg binarized | 1.58±3.46 | 0.95 (<.001) | 0.94 (<.001) | 0.937 (0.935–0.939) |
| TIV | ||||
| CTSeg-probabilistic | –12.15±1.44 | 0.99 (<.001) | 0.71 (<.001) | 0.685 (0.680–0.689) |
| CTSeg binarized | –3.28±1.36 | 0.99 (<.001) | 0.97 (<.001) | 0.962 (0.961–0.963) |
| BET | –5.12±0.667 | 0.99 (<.001) | 0.94 (<.001) | 0.930 (0.928–0.932) |
↵a %Difference is reported as means.