Five different types of normal-appearing cerebellar damage in NMOSD
| Types of Occult Cerebellar Damage | SCI vs HC | AQP4-Ab (+) vs HC | ||
|---|---|---|---|---|
| Without Controlling for AQP4-Ab Status | Controlling for AQP4-Ab Status | Without Controlling for LSCL | Controlling for LSCL | |
| Type 1: only related to spinal lesions | Significant or not | Significant | Nonsignificant | Nonsignificant |
| Type 2: only related to AQP4-Ab | Nonsignificant | Nonsignificant | Significant or not | Significant |
| Type 3: mainly related to spinal lesions | Significant | Nonsignificant | Nonsignificant | Nonsignificant |
| Type 4: mainly related to AQP4-Ab | Nonsignificant | Nonsignificant | Significant | Nonsignificant |
| Type 5: no cerebellar damage | Nonsignificant | Nonsignificant | Nonsignificant | Nonsignificant |
Note:—+ indicates seropositive.