Selected patient characteristics from the overall patient population and in patients with and without FHPa
| Variable | Population (n = 2216) | FHP (n = 1624) | No FHP (n = 592) | Odds Ratio | 95% CI |
|---|---|---|---|---|---|
| Demographics | |||||
| Age (yr) | 71.4 (20) | 72 (19.5) | 69.7 (21) | 1.01b | 1.00–1.01 |
| Female sex | 958 (43.3) | 723 (44.6) | 235 (39.8) | 1.22b | 1.01–1.48 |
| Preexisting mRS score | 0 (1) | 0 (1) | 0 (1) | 0.96 | 0.87–1.05 |
| Anticoagulation at onset | 211 (9.6) | 158 (9.8) | 53 (9) | 1.10 | 0.80–1.54 |
| Clinical presentation | |||||
| Admission NIHSS (points) | 8 (11) | 10 (12) | 4 (4) | 1.21b | 1.18–1.24 |
| Aphasia | 831 (38) | 743 (46.4) | 88 (15) | 4.91b | 3.85–6.32 |
| Hemineglect | 583 (26) | 555 (35) | 28 (4.8) | 10.70b | 7.36–16.2 |
| Decreased level of consciousness | 252 (11.6) | 226 (14.3) | 26 (4.5) | 3.58b | 2.40–5.55 |
| Sensory deficit | 1237 (56.9) | 1021 (64.1) | 216 (37.1) | 3.03b | 2.49–3.69 |
| Visual field defect | 882 (40.6) | 836 (52.6) | 46 (7.9) | 13.00b | 9.58–18.07 |
| Stroke localization | |||||
| Pure posterior circulation | 394 (18) | 182 (11.3) | 212 (36.9) | 0.22b | 0.17–0.27 |
| Pure anterior circulation | 1657 (75.4) | 1393 (86.6) | 254 (44.3) | 8.12b | 6.54–10.12 |
| Stroke mechanism | |||||
| Atherosclerotic | 301 (14.1) | 249 (15.8) | 52 (9.2) | 1.87b | 1.37–2.58 |
| Cardioembolic | 729 (34) | 633 (40.2) | 96 (16.9) | 3.31b | 2.61–4.23 |
| Lacunar | 238 (11.1) | 42 (2.7) | 196 (34.5) | 0.05b | 0.04–0.07 |
| Risk factors | |||||
| Atrial fibrillation | 619 (28) | 536 (33.1) | 83 (14) | 3.03b | 2.36–3.92 |
| Hypercholesterolemia | 1606 (73.1) | 1147 (71.2) | 459 (78) | 0.70b | 0.56–0.87 |
| Acute CT imaging | |||||
| Onset-to-CT time (hr) | 4.3 (10.4) | 3.5 (8.6) | 8.1 (12.9) | 0.96b | 0.95–0.97 |
| Early ischemic changes on NCCT | 831 (38.2) | 771 (48.5) | 60 (10.3) | 8.20b | 6.21–10.99 |
| Arterial pathology in ischemic territory | 242 (16.2) | 237 (20.7) | 5 (1.4) | 18.01b | 8.19–50.89 |