Table 1:

Patient characteristics and temperature profilea

Characteristics
Mean age (yr)65 (range, 18–94)
NIHSS score18 (14–22)
Women60 (46.5%)
Presentation core infarction volumeb9.6 mL (1.5–25.3)
Hypoperfused volumec132.6 mL (84.2–204)
Occluded vesselsn (%)
    Intracranial ICA17 (13.2%)
    Extracranial ICA2 (1.6%)
    M1 MCA63 (48.8%)
    M2 MCA24 (18.6%)
    ACA4 (3.1%)
    Vertebrobasilar1 (0.8%)
    Tandem18 (14%)
Reperfusion score
    mTICI 2b67 (52.9%)
    mTICI 362 (48.1%)
Last known well to reperfusion414 min (295–572)
CTP to reperfusion119 min (84–162)
Procedure time to reperfusion58.0 min (38.5–94.5)
Total procedural duration77 min (51–118)
CTP-to-MRI time26.8 hr (20–47.2)
Last known well to MRI30.6 hr (24.0–51.2)
General anesthesia (No.)44 (34.1%)
Aspirin therapy (No.)125 (96.9%)
Received acetaminophen (No.)91 (70.5%)
Final infarct volume19.6 mL (8.3–45.2 mL)
Mean 90-day mRS2
Favorable clinical outcome (mRS ≤2) (No.)77 (59.7%)
90-day mortality (No.)11 (8.5%)
Population temperature minima (mean)35.3°C
Population temperature maxima (mean)37.9°C
Per-patient temperature fluctuation2.4°C (1.8°C–3.3°C)
Temperature increase from baseline1.6°C (1.0°C–2.5°C)

  • Note:—ACA indicates anterior cerebral artery.

  • ↵a Data are reported as proportions and median (IQR), unless otherwise stated.

  • ↵b Relative cerebral blood flow <30% of contralateral normal tissues.

  • ↵c Tmax of >6 seconds.