Sensitivity and specificity for various MRI criteria with or without rim lesions
| Criteria | % Subjects with MS | % Total PC Subjects | % Indeterminate PC Subjects | % Definite PC Subjects | Sensitivitya | Specificitya |
|---|---|---|---|---|---|---|
| Rim lesions alone | ||||||
| 1+ rim | 97% (104/107) | 22% (8/36) | 80% (8/10) | 0% (0/26) | 97% | 78% |
| 2+ rims | 88% (94/107) | 3% (1/36) | 10% (1/10) | 0% (0/26) | 88% | 97% |
| Involving DIS 20011 | ||||||
| MRI-DIS only | 77% (82/107) | 44% (16/36) | 20% (2/10) | 54% (14/26) | 77% | 56% |
| MRI-DIS + 1+ rim | 76% (81/107) | 6% (2/36) | 20% (2/10) | 0% (0/26) | 76% | 94% |
| MRI-DIS + 2+ rims | 71% (76/107) | 0% (0/36) | 0% (0/10) | 0% (0/26) | 71% | 100% |
| MRI-DIS + 3+ rims | 65% (70/107) | 0% (0/36) | 0% (0/10) | 0% (0/26) | 65% | 100% |
| Involving DIS 20102 | ||||||
| MRI-DIS only | 100% (107/107) | 83% (30/36) | 60% (6/10) | 92% (24/26) | 100% | 17% |
| MRI-DIS + 1+ rim | 97% (104/107) | 17% (6/36) | 60% (6/10) | 0% (0/26) | 97% | 83% |
| MRI-DIS + 2+ rims | 88% (94/107) | 3% (1/36) | 10% (1/10) | 0% (0/26) | 88% | 97% |
| MRI-DIS + 3+ rims | 73% (78/107) | 0% (0/36) | 0% (0/10) | 0% (0/26) | 73% | 100% |
↵a Based on the total PC group.