Spinal MRI findings in AQP4 antibody–positive and –negative groupsa
| Imaging Features | AQP4 Antibody–Positive Group (n = 15) | AQP4 Antibody–Negative Group (n = 26) |
|---|---|---|
| Cervicomedullary junction involvement | 9 (60%) | 6 (23%) |
| Medulla oblongata involvement | 4 (27%) | 1 (4%) |
| Cord expansion ratio (mean) (onset ≤2 months)b | 1.35 ± 0.15 | 1.24 ± 0.15 |
| Cord expansion ratio (mean) (onset ≤15 days)c | 1.34 ± 0.17 | 1.24 ± 0.17 |
| Bright spotty lesion | ||
| Negative | 1 (7%) | 18 (69%) |
| Positive | 14 (93%) | 8 (31%) |
| Involved segment | ||
| Cervical | 5 (33%) | 7 (27%) |
| Cervicothoracic | 8 (53%) | 5 (19%) |
| Thoracic | 2 (13%) | 10 (38%) |
| Thoracolumbar | 0 (0%) | 1 (4%) |
| Holocord | 0 (0%) | 3 (12%) |
| No. of segments involved (mean) | 9 ± 4 | 7 ± 4 |
| Axial distribution | ||
| Central | 10 (67%) | 21 (81%) |
| Peripheral | 4 (27%) | 4 (15%) |
| Both | 1 (7%) | 1 (4%) |
| >Half of the cord area | 12 (80%) | 24 (92%) |
| Enhancement | ||
| No enhancement | 4 (27%) | 6 (23%) |
| <50% enhancement | 9 (60%) | 17 (65%) |
| >50% enhancement | 0 (0%) | 0 (0%) |
| Not available | 2 (13%) | 3 (12%) |