Table 1:

Comparison of demographic and clinical data for HCs and subjects with RRMS and SPMSa

ParameterHC (n = 19)RRMS (n = 19)SPMS (n = 20)RRMS vs HC (P Value)SPMS vs HC (P Value)SPMS vs RRMS (P Value)
Age (yr)49.0 ± 7.146.4 ± 7.255.2 ± 6.5.27.0168b.0041b
Sex (F/M)14:515:411:9.70.23.12
Education (yr)16.9 ± 2.916.1 ± 1.315.1 ± 2.6.22.051.15
Disease duration (yr)0.0011.8 ± 5.416.7 ± 6.5NANA.0234
EDSS (median) (IQR)0.001.5 (1–2)6 (6–6.5)NANA.0006b

  • Note:—IQR indicates interquartile range; NA, not applicable.

  • ↵a All values are mean (SD) except where indicated. Bonferroni corrected P < .017 is considered statistically significant.

  • ↵b Significant.