Diagnostic performance of MR imaging for the discrimination of early NPC from BH
| Volume | Size Asymmetry | Signal Asymmetry | Deep Mucosal White Line | Adenoid | |
|---|---|---|---|---|---|
| Test positive for NPC | Volume ≥ 5.01 cm3 | %ΔA ≥ 33.7% | Signal asymmetry present | Focal loss of the deep mucosal white line | Septa absent or distorted (excluding septa distorted by cysts) |
| n = 333 (NPC = 189, BH = 144) | n = 333 (NPC = 189, BH = 144) | n = 333 (NPC = 189, BH = 144) | n = 253 (NPC = 180, BH2 = 73) | n = 172 (NPC = 111, BH2 = 61) | |
| Area under the curve (95% CI) | 0.676 (0.618–0.734) | 0.948 (0.926–0.971) | |||
| P value | <.001 | <.001 | |||
| True-positive (No.) | 119 | 167 | 161 | 153 | 111 |
| False-positive (No.) | 47 | 13 | 26 | 10 | 9 |
| True-negative (No.) | 97 | 131 | 118 | 63 | 52 |
| False-negative (No.) | 70 | 22 | 28 | 27 | 0 |
| Sensitivity (%) | 63.0 | 88.4 | 85.2 | 85.0 | 100.0 |
| Specificity (%) | 67.4 | 91.0 | 81.9 | 86.3 | 85.2 |
| Positive predictive value (%) | 71.7 | 92.8 | 86.1 | 93.9 | 92.5 |
| Negative predictive value (%) | 58.1 | 85.6 | 80.8 | 70.0 | 100.0 |
| Accuracy (%) | 64.9 | 89.5 | 83.8 | 85.4 | 94.8 |