Table 3:

Diagnostic predictive values for the differentiation of hemangioblastomas from metastasesa

Reading Session and StatisticObserver 1Observer 2
Conventional image set
    AUCb0.594 (0.400–0.768)0.683 (0.489–0.840)
    Sensitivity (%)18.8 (3/16)43.7 (7/16)
    Specificity (%)100 (14/14)92.9 (13/14)
    Accuracy (%)57 (17/30)67 (20/30)
Combined ASL image set
    AUCb0.969 (0.831–0999)1.000 (0.884–1.000)
    Sensitivity (%)93.7 (15/16)100 (16/16)
    Specificity (%)100 (14/14)100 (14/14)
    Accuracy (%)97 (29/30)100 (30/30)
P value for pair-wise comparison of ROC curves<.001<.0001
P value calculated with the McNemar test for the comparison of accuracy<.001.022

  • ↵a Unless otherwise indicated, the numbers in parentheses are raw data. Sensitivity, specificity, and accuracy were calculated under the assumption that a confidence score of 4 or higher was considered positive for the diagnosis of hemangioblastoma.

  • ↵b Data in parentheses are 95% CIs.