Characteristics at diagnosis of the 31 patients with primary central nervous system vasculitisa
| Characteristics | Total (n = 31) | Unenrolled Patients (n = 54) | P Value |
|---|---|---|---|
| Demographic data | |||
| Age (yr) | 42 (24–65) | 46 (18–79) | .73 |
| Male/female | 16:15 | 28:26 | .98 |
| Clinical manifestations | |||
| Headaches | 17 (55) | 42 (78) | .03 |
| Focal deficits | 26 (84) | 43 (80) | .63 |
| Seizures | 9 (29) | 22 (41) | .28 |
| Cognitive impairment | 7 (23) | 26 (48) | .02 |
| Loss of consciousness | 3 (10) | 19 (35) | .01 |
| Psychiatric disorders | 6 (19) | 13 (24) | .61 |
| C-reactive protein, (mg/L) | 3 (0–47) | 5 (1–95) | .13 |
| Abnormal CSF | 18/29 (62) | 35/53 (66) | .13 |
| Leukocyte count (/mm3) | 6 (1–100) | 8 (0–250) | .07 |
| Protein concentration (mg/mL) | 0.6 (0.2–4.1) | 0.7 (0.1–2.8) | .19 |
| Abnormal brain biopsy findings | 8/16 (50) | 18/26 (69) | .32 |
| Abnormal DSA findings | 25 (81) | 26/41 (63) | .13 |
| Abnormal MRA findings | 24 (77) | 25/44 (57) | .09 |
↵a Unless otherwise indicated, values are an absolute number (%) or median (range).