Sensitivity, specificity, and accuracy of early and term MRI scores categorized as moderate/severe to predict an outcome of < −1 SD on the Bayley III or NSMDA functional classification of mild-profound dysfunctiona
| 12-Month Neurodevelopmental Outcome | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Bayley III Motor Composite Score | Bayley III Cognitive Composite Score | NSMDA | |||||||
| Sensitivity | Specificity | Correctly Classified | Sensitivity | Specificity | Correctly Classified | Sensitivity | Specificity | Correctly Classified | |
| Early MRI (n = 83) | |||||||||
| WM | 33 (12–62) | 78 (66–87) | 70 | 50 (12–88) | 78 (67–87) | 76 | 43 (10–82) | 78 (67–86) | 75 |
| CGM | 0 (0–22) | 81 (70–89) | 66 | 0 (0–46) | 83 (73–91) | 77 | 0 (0–41) | 83 (73–91) | 76 |
| DGM | 40 (16–68) | 94 (86–98) | 84 | 33 (4–78) | 90 (81–95) | 86 | 43 (10–82) | 91 (82–96) | 87 |
| Cerebellum | 13 (2–40) | 93 (84–98) | 78 | 17 (1–64) | 92 (84–97) | 87 | 29 (4–71) | 93 (85–98) | 88 |
| Global score | 33 (12–62) | 87 (76–94) | 77 | 50 (12–88) | 86 (76–93) | 83 | 43 (10–82) | 86 (76–93) | 82 |
| Term MRI (n = 77) | |||||||||
| WM | 14 (2–43) | 92 (82–97) | 78 | 33 (4–78) | 93 (84–98) | 88 | 29 (4–71) | 93 (84–98) | 87 |
| CGM | 21 (5–51) | 79 (67–89) | 69 | 0 (0–46) | 77 (66–87) | 71 | 29 (4–71) | 80 (69–89) | 75 |
| DGM | 36 (13–65) | 86 (75–93) | 77 | 33 (4–78) | 83 (72–91) | 79 | 71 (29–96) | 87 (77–94) | 86 |
| Cerebellum | 21 (5–51) | 92 (82–97) | 79 | 33 (4–78) | 92 (83–97) | 87 | 43 (10–82) | 93 (84–98) | 88 |
| Global score | 14 (2–43) | 90 (80–96) | 77 | 33 (4–78) | 92 (83–97) | 87 | 29 (4–71) | 91 (82–97) | 86 |
↵a Sensitivity and specificity are percentage (95% CI); “Correctly Classified” is percentage; early MRI, 29 to 35 weeks PMA; term MRI, 40 to 42 weeks PMA.