Table 2:

Risk of vascular events by anatomic location^{^a}

	All Deaths	Vascular Death	Myocardial Infarction	Any Stroke	Any Vascular Event
Small PVS score
Basal ganglia	1.01, 0.95–1.08	1.12, 1.02–1.22	1.06, 0.94–1.19	1.00, 0.90–1.12	1.06, 1.00–1.13
Subcortical	1.01, 0.95–1.07	1.06, 0.99–1.14	1.01, 0.94–1.12	1.08, 1.00–1.16	1.05, 0.99–1.14
Posterior fossa	1.02, 0.80–1.36	1.19, 0.79–1.76	1.26, 0.83–1.91	1.09, 0.70–1.67	1.09, 0.83–1.44
Large PVS score
Subcortical white matter	0.68, 0.43–1.07	0.81, 0.42–1.47	1.26, 0.85–1.85	1.32, 0.95–1.85	1.08, 0.79–1.47
Subinsular	0.94, 0.80–1.10	1.21, 0.92–1.39	1.10, 0.84–1.43	1.08, 0.80–1.45	1.11, 0.93–1.30
Basal ganglia supraputaminal	1.73, 1.07–2.77	0.54, 0.22–2.25	1.17, 0.31–4.37	1.45, 0.61–3.43	0.90, 0.40–1.91
Basal ganglia infraputaminal	1.05, 0.88–1.25	1.24, 0.93–1.66	0.98, 0.63–1.46	0.92, 0.70–1.22	1.09, 0.89–1.33

↵a Models are adjusted for head size, motion artifacts, age, sex, ethnicity, vascular risk factors at MRI and during follow-up (hypertension, hypercholesterolemia, diabetes, smoking), prior cardiac disease, and body mass index. Data are hazard ratios and 95% CIs.