Stratified risk model by tertiles of pulse pressure and systolic blood pressurea
| Stratified by | Low Tertile | Middle Tertile | High Tertile |
|---|---|---|---|
| Pulse pressure at MRI | |||
| Small PVS score | |||
| Vascular death | 1.07 (0.96–1.18) | 1.05 (0.96–1.14) | 1.08 (1.01–1.17) |
| Any stroke | 1.01 (0.90–1.13) | 1.03 (0.90–1.18) | 1.07 (0.98–1.16) |
| Any vascular event | 1.05 (0.98–1.13) | 1.02 (0.96–1.09) | 1.05 (0.99–1.10) |
| Systolic blood pressure at MRI | |||
| Small PVS score | |||
| Vascular death | 1.08 (0.99–1.18) | 0.96 (0.86–1.08) | 1.11 (1.04–1.20) |
| Any stroke | 1.05 (0.94–1.17) | 0.95 (0.83–1.09) | 1.08 (1.01–1.16) |
| Any vascular event | 1.05 (0.98–1.12) | 1.02 (0.95–1.09) | 1.05 (1.00–1.11) |
↵a Models are adjusted for head size, motion artifacts, age, sex, ethnicity, vascular risk factors at MRI and during follow-up (hypertension, hypercholesterolemia, diabetes, and smoking), prior cardiac disease, and body mass index. Data are hazard ratios and 95% CIs.