Table 5:

Intergroup differences of the AD and RD values that contributed to the altered MD valuesa

T2DM (n = 58)Healthy Controls (n = 58)FP
Superior rPF_WM
    AD, ×10−5 mm2/s111.06 ± 6.52105.23 ± 4.2531.431<.001
    RD, ×10−5 mm2/s93.28 ± 6.4187.75 ± 4.4928.488<.001
Middle rPF_WM
    AD, ×10−5 mm2/s113.59 ± 6.04108.52 ± 3.4831.472<.001
    RD, ×10−5 mm2/s90.12 ± 6.3985.27 ± 3.5327.982<.001
Inferior rPF_WM
    AD, ×10−5 mm2/s116.85 ± 5.98112.19 ± 5.5318.548<.001
    RD, ×10−5 mm2/s84.53 ± 5.9581.24 ± 4.3810.752.001
lPF_WM
    AD, ×10−5 mm2/s121.75 ± 10.54114.50 ± 6.6219.725<.001
    RD, ×10−5 mm2/s107.47 ± 11.4098.84 ± 7.4423.252<.001
rST_WM
    AD, ×10−5 mm2/s127.10 ± 10.59119.03 ± 6.3822.413<.001
    RD, ×10−5 mm2/s102.70 ± 10.2594.47 ± 5.8525.394<.001
Splenium of CC
    AD, ×10−5 mm2/s269.21 ± 20.44255.20 ± 24.279.865.002
    RD, ×10−5 mm2/s152.25 ± 32.11127.36 ± 32.8415.805<.001
lEC
    AD, ×10−5 mm2/s122.54 ± 7.42117.14 ± 4.8421.495<.001
    RD, ×10−5 mm2/s92.85 ± 8.7086.36 ± 6.1422.007<.001
Pons
    AD, ×10−5 mm2/s222.11 ± 27.07201.58 ± 26.1518.416<.001
    RD, ×10−5 mm2/s177.25 ± 27.60157.84 ± 24.3817.237<.001

  • Note:—lPF_WM indicates left prefrontal white matter; rST_WM, right superior temporal white matter.

  • ↵a Data are presented as mean ± SD. The intergroup comparisons were performed with ANCOVA adjusted for age, sex, and years of education.