Table 4:

Clinicoradiologic correlation using 3D-GE and 2D-SE normalized subcortical structure values obtained with FIRST software

Subcortical Structure	FIRST 3D-GE				FIRST 2D-SE
	Disease Duration		EDSS		Disease Duration		EDSS
	r	P	ρ	P	r	P	ρ	P
Brain stem	−0.133	.433	−0.160	.345	0.079	.674	−0.150	.420
L thalamus	−0.424^{^a}	.009^{^a}	−0.226	.170	0.053	.777	0.080	.671
L caudate	−0.410^{^a}	.012^{^a}	−0.302^{^b}	.069^{^b}	−0.297	.105	−0.065	.728
L putamen	−0.383^{^a}	.019^{^a}	−0.364^{^a}	.027^{^a}	−0.056	.767	−0.262	.154
L pallidum	−0.308^{^b}	.063^{^b}	−0.430^{^a}	.008^{^a}	−0.073	.696	−0.002	.991
L hippocampus	−0.429^{^a}	.008^{^a}	−0.170	.313	−0.226	.222	−0.083	.658
L amygdala	−0.276^{^b}	.098^{^b}	−0.029	.864	0.195	.294	0.230	.213
L accumbens	−0.234	.164	−0.30^{^b}	.071^{^b}	0.384^{^a}	.033^{^a}	0.023	.901
R thalamus	−0.496^{^a}	.002^{^a}	−0.235	.162	−0.022	.905	−0.092	.621
R caudate	−0.501^{^a}	.002^{^a}	−0.270^{^a}	.106^{^a}	−0.419^{^a}	.019^{^a}	−0.188	.310
R putamen	−0.406^{^a}	.013^{^a}	−0.454^{^a}	.005^{^a}	−0.043	.817	−0.286	.119
R pallidum	−0.288^{^b}	.08^{^b}	−0.36^{^b}	.029^{^b}	−0.005	.980	0.013	.945
R hippocampus	−0.384^{^a}	.019^{^a}	−0.002	.988	−0.082	.662	−0.064	.731
R amygdala	−0.253	.131	0.046	.785	0.027	.887	0.331	.069
R accumbens	−0.316^{^b}	.057^{^b}	−0.322	.052	0.233	.208	−0.014	.941

Note:—L indicates left; R, right; r, the Pearson correlation coefficient; ρ, the Spearman correlation coefficient.
↵a Significant correlations.
↵b Trend toward a significant correlation.