Clinical characteristics of patients who presented with type III lesionsa
| Patient | Sex/Age (yr) | Symptoms | Lesion Location | Lesion Size (cm) | Durationb (mo) to Classic GB | IDH1 Mutation |
|---|---|---|---|---|---|---|
| 1 | F/95 | Facial palsy | Right frontal | 3 × 1.5 | 3 | NS |
| 2 | M/48 | Generalized seizure | Right frontal | 4 × 2 | NA | − |
| 3 | M/69 | Focal seizure | Right parietal | 2.5 × 1.2 | 3 | − |
| 4 | F/59 | Slurred speech | Left insular | 3 × 1.3 | NA | NS |
| 5 | F/55 | Hand numbness | Right parietal | 2.1 × 1.3 | NA | − |
| 6 | F/69 | Leg weakness | Right frontal | 3 × 1.2 | NA | NS |
| 7 | F/35 | Leg numbness | Left frontal | 2.5 × 1.3 | 1 | − |
| 8 | M/65 | Generalized seizure | Left parietal | 2.6 × 2.6 | NA | NS |
| 9 | M/45 | Generalized seizure | Left temporal | 3 × 3 | 1 | NS |
| 10 | M/58 | Generalized seizure | Left frontal | 1.5 × 1 | NA | NS |
| 11 | M/43 | Generalized seizure | Left frontal | 3 × 1.8 | NA | NS |
| 12 | M/62 | Generalized seizure | Left temporal | 2.4 × 2.3 | 6 | − |
Note:—NA indicates not available; NS, not studied; −, negative.
↵a The lesions refer to FLAIR/T2-weighted hyperintensities involving the cortex and subcortical WM, with focal contrast enhancement at the GM-WM junction. The size of contrast-enhancing foci is not shown because they are about ≤1 cm.
↵b The duration is the time interval between the first and follow-up MR imaging studies showing classic GB. NA indicates that type III lesions were resected before progressing to classic GB.