Table 2:

Quantitative BBBP and CTP resultsa

GCENon-GCEP Value
Kep (min−1)1.28 (1.23–1.33)1.52 (1.45–1.59)<.0001
Ktrans (min−1)0.15 (0.14–0.16)0.19 (0.18–0.20)<.0001
PS (mL × mL−1 × min−1)227.4 (213.4–241.5)208.4 (189.7–227.2).1095
VE0.70 (0.61–0.78)0.39 (0.36–0.42)<.0001
VP0.51 (0.48–0.53)0.57 (0.54–0.60).0019
F (mL × mL−1 × min−1)1175 (1125–1226)1329 (1259–1398).0005
CBF (mL × 100 g−1 × min−1)32.57 (28.20–36.93)42.02 (35.44–48.60).0148
CBV (mL × 100 g−1)5.86 (4.76–6.96)5.86 (4.16–7.56).9950
MTT (s)2.28 (1.44–3.12)2.20 (1.99–2.40).8376
  • a Data presented as mean (95% CI).