Table 2:

Quantitative BBBP and CTP results^{^a}

	GCE	Non-GCE	P Value
K_ep (min⁻¹)	1.28 (1.23–1.33)	1.52 (1.45–1.59)	<.0001
K^trans (min⁻¹)	0.15 (0.14–0.16)	0.19 (0.18–0.20)	<.0001
PS (mL × mL⁻¹ × min⁻¹)	227.4 (213.4–241.5)	208.4 (189.7–227.2)	.1095
VE	0.70 (0.61–0.78)	0.39 (0.36–0.42)	<.0001
VP	0.51 (0.48–0.53)	0.57 (0.54–0.60)	.0019
F (mL × mL⁻¹ × min⁻¹)	1175 (1125–1226)	1329 (1259–1398)	.0005
CBF (mL × 100 g⁻¹ × min⁻¹)	32.57 (28.20–36.93)	42.02 (35.44–48.60)	.0148
CBV (mL × 100 g⁻¹)	5.86 (4.76–6.96)	5.86 (4.16–7.56)	.9950
MTT (s)	2.28 (1.44–3.12)	2.20 (1.99–2.40)	.8376

↵a Data presented as mean (95% CI).