Commonly used quantitative parameters in the DCE-MRI pharmacokinetic analysis
| Parameter | Definition | Units |
|---|---|---|
| Ktrans | Volume transfer constant between EES and blood plasma | Min−1 |
| Ve | EES volume per unit tissue volume | NA |
| Vp | Blood plasma volume per unit tissue volume | NA |
| Kep or K21 | Rate constant from EES to blood plasma | Min−1 |
| Kpe or K12 | Rate constant from blood plasma to EES | Min−1 |
| Kel | Elimination rate constant | Min−1 |
| Amp or AH | Amplitude of the normalized dynamic curve | NA |
Note:—Amp or AH, amplitude of the normalized dynamic curve; NA, not applicable; Min, minute.