Correlation coefficients (P values) for semipartial correlations after adjusting MRI parameters for age and EDSS for disease duration
GP | Put | Cau | Aput | Pput | |
---|---|---|---|---|---|
Sqrt (Flanker) vs age-adjusted QSM | 0.26 (.18) | 0.36 (.063) | 0.51 (.0058)a | 0.45 (.016)a | 0.26 (.17) |
Sqrt (Flanker) vs age-adjusted R2 | 0.33 (.09) | 0.34 (.08) | 0.31 (.11) | 0.37 (.056) | 0.23 (.25) |
Duration-adjusted EDSS vs age-adjusted QSM | 0.00 (.98) | 0.39 (.036)a | 0.01 (.95) | 0.34 (.07) | 0.40 (.032)a |
Duration-adjusted EDSS vs age-adjusted R2 | 0.16 (.43) | 0.51 (.0059)a | 0.46 (.014)a | 0.51 (.0054)a | 0.44 (.019)a |
Note:—Sqrt indicates the square root transformation used for the non-normal distributed Flanker test metrics; Cau, caudate; Put, putamen; Aput, cognitive anterior part of putamen, region predominantly connected to frontal cortex; Pput, motor posterior part of putamen, region predominantly connected to sensorimotor cortex.
↵a Statistically significant at P < .05.