Bivariate Pearson correlation coefficients (P values) (n = 29 except as noted)
| Age | Durationa | EDSS | Flankerb | Stroopc | |
|---|---|---|---|---|---|
| QSM | |||||
| GP | 0.36 (.059) | 0.10 (.60) | 0.06 (0.75) | 0.25 (.20) | −0.18 (.36) |
| Put | 0.57 (.001)f | 0.04 (.85) | 0.31 (0.09) | 0.3 (.12) | 0.01 (.97) |
| Cau | 0.41 (.02)f | 0.42 (.02)f | 0.24 (0.20) | 0.47 (.01)f | 0.13 (.50) |
| Aput | 0.55 (.0015)f | 0.05 (.81) | 0.30 (0.11) | 0.38 (.045)f | 0.00 (.99) |
| Pput | 0.57 (.001)f | 0.09 (.65) | 0.35 (0.06) | 0.23 (.25) | −0.01 (.94) |
| R2 | |||||
| GPd | 0.32 (.12) | 0.08 (.68) | 0.18 (0.38) | 0.32 (.11) | 0.065 (.76) |
| Pute | 0.47 (.01)f | 0.09 (.65) | 0.43 (0.02)f | 0.31 (.11) | 0.21 (.34) |
| Caue | 0.37 (.06) | 0.29 (.15) | 0.58 (.001)f | 0.31 (.11) | 0.07 (.75) |
| Apute | 0.44 (.02)f | 0.12 (.54) | 0.48 (.01)f | 0.35 (.08) | 0.17 (.44) |
| Ppute | 0.47 (.01)f | 0.01 (.96) | 0.32 (.04)f | 0.21 (.29) | 0.28 (.18) |
| R2* | |||||
| GP | 0.14 (.45) | −0.23 (.22) | −0.20 (.29) | 0.2 (.3) | −0.24 (.22) |
| Put | 0.38 (.047)f | −0.12 (.51) | 0.25 (.19) | 0.34 (.075) | −0.02 (.92) |
| Cau | 0.29 (.12) | −0.02 (.90) | 0.24 (.20) | 0.29 (.13) | 0.27 (.17) |
| Aput | 0.30 (.11) | −0.15 (.43) | 0.26 (.16) | 0.37 (.055) | −0.04 (.84) |
| Pput | 0.45 (.01)f | −0.06 (.74) | 0.17 (.36) | 0.23 (.23) | −0.00 (.99) |
Note:—Cau indicates caudate; Put, putamen; Aput, cognitive anterior part of putamen, region predominantly connected to frontal cortex; Pput, motor posterior part of putamen, region predominantly connected to sensorimotor cortex.
↵a Using square root transformation for non-normal duration data.
↵b Using square root transformation for non-normal Flanker measure (n = 28).
↵c Stroop measure (n = 27).
↵d For GP R2 n = 27 so that R2–GP versus Flanker (n = 26).
↵e For putamen and caudate R2 n = 28 so that R2–Put, R2–Cau versus Flanker (n = 27).
↵f Statistically significant at P < .05.