Table 1:

General patient characteristics

CharacteristicHPV-Positive (n = 22) (50%)HPV-Negative (n = 22) (50%)P Value
Sex.30
    Male18 (81.8%)15 (68.2%)
    Female4 (18.2%)7 (31.8%)
Age at diagnosis (yr).92
    Median (range)57 (47–78)60.5 (45–71)
Oropharyngeal subsite.29
    Tonsil12 (54.4%)10 (45.5%)
    Base of tongue8 (36.4%)6 (27.3%)
    Oropharynx nos2 (9.1%)6 (27.3%)
Smokinga.01
    Never (0–5 pack years)8 (36.4%)0 (0%)
    Moderate (6–24 pack years)5 (22.7%)5 (22.7%)
    Heavy (>24 pack years)9 (40.9%)17 (77.3%)
Alcohol consumptionb.02
    Never (0)3 (13.6%)0 (0%)
    Moderate (1–149 U years)15 (68.2%)10 (45.5%)
    Heavy (>149 U years)4 (18.2%)12 (54.5%)
T-stage.03
    T212 (54.5%)5 (22.7%)
    T3–410 (45.5%)17 (77.3%)
N-stage.04
    N00 (0%)5 (22.7%)
    N1–322 (100%)17 (77.3%)
M-stageNA
    M022 (100%)22 (100%)
    M10 (0%)0 (0%)

  • Note:—NA indicates not applicable; Oropharynx nos, oropharynx not otherwise specified.

  • ↵a Smoking was defined in pack years (1 pack year = 20 cigarettes a day during 1 year).

  • ↵b Alcohol consumption was defined in unit years (1 U year = 1 alcohol-containing consumption a day during 1 year).