Global tissue volumes normalized to total intracranial volume
| Nonimpaired (n = 20) | Cognitively Impaired (n = 25) | P Value | |
|---|---|---|---|
| Normalized GM volume (%) | 42.3 (41.8–43.0) | 41.0 (39.7–42.2) | .003a |
| Normalized WM volume (%) | 34.6 (33.9–35.4) | 34.4 (34.0–35.3) | .664a |
| Normalized WML volume (%) | 0.3 (0.0–1.1) | 1.3 (0.6–1.9) | .002a |
↵a Wilcoxon rank sum test (median [interquartile range]).