Synopsis of clinical and perfusion data in 20 patients
| No. | Perfusion Abnormality | Time to Imaginga | Clinical Symptomsb | TTPc | rMTT | rCBF | rCBV | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| VS | AP | PA | MD | N | V | Ant | Med | Post | Ant | Med | Post | Ant | Med | Post | Ant | Med | Post | |||
| 1 | Yes | 60 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 3 | 3 | 0 | 2 | 2 | 0 | 2 | 2 | 0 | 1 | 1 |
| 2 | Yes | 60 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 3 | 3 | 0 | 2 | 2 | 0 | 2 | 2 | 0 | 1 | 1 |
| 3 | No | 360 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 4 | No | 240 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 5 | Yes | 60 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 3 | 3 | 0 | 2 | 2 | 0 | 2 | 2 | 0 | 1 | 1 |
| 6 | Yes | 240 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 3 | 3 | 0 | 3 | 3 | 0 | 0 | 0 | 0 | 0 | 0 |
| 7 | No | 300 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 8 | Yes | 210 | 1 | 1 | 1 | 0 | 0 | 0 | 3 | 3 | 3 | 2 | 2 | 2 | 2 | 2 | 2 | 1 | 1 | 1 |
| 9 | Yes | 198 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 3 | 3 | 0 | 3 | 3 | 0 | 2 | 2 | 0 | 1 | 1 |
| 10 | No | 120 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 11 | Yes | 100 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 2 | 2 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 |
| 12 | Yes | 100 | 1 | 0 | 1 | 1 | 1 | 1 | 3 | 3 | 3 | 3 | 3 | 3 | 2 | 2 | 2 | 1 | 1 | 1 |
| 13 | Yes | 60 | 0 | 1 | 0 | 0 | 0 | 0 | 3 | 3 | 3 | 3 | 3 | 3 | 2 | 2 | 2 | 1 | 1 | 1 |
| 14 | Yes | <6 hr | 0 | 1 | 0 | 0 | 1 | 0 | 3 | 3 | 3 | 2 | 2 | 2 | 1 | 1 | 1 | 0 | 0 | 0 |
| 15 | Yes | 80 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 16 | Yes | 72 hr | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 3 | 3 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 |
| 17 | Yes | <6 hr | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 3 | 3 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 |
| 18 | No | 360 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 19 | No | 210 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 20 | Yes | 200 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 3 | 3 | 0 | 2 | 2 | 0 | 2 | 2 | 0 | 1 | 1 |
| Mean grade score | 0.60 | 1.95 | 1.95 | 0.50 | 1.40 | 1.40 | 0.35 | 1.00 | 1.00 | 0.15 | 0.50 | 0.50 | ||||||||
| Total mean grade score | 1.50 | 1.10 | 0.78 | 0.38 | ||||||||||||||||
Note:—VS indicates visual symptoms; AP, aphasia; PA, paresthesias; MD, motor disabilities; N: nausea; V, vertigo; Ant, anterior; Med, middle; Post, posterior.
↵a Time to imaging is the interval between onset of symptoms and beginning of MRI study, given in minutes.
↵b History of migraine is the available clinical history of migraine at the time of initial neurologic examination.
↵c Perfusion abnormalities on visual assessment for all patients according to the vascular territories using a 4-point scale (0 = no abnormality, 3 = major abnormality).