Recently completed and ongoing intracranial aneurysm RCTs^a

Trial	Comparison	Simple or Composite	“Recurrence” as Angiographic Outcome	Recurrence Scale	“Other” Angiographic Primary Outcome	Retreatment as Primary Outcome	Duration for Primary Outcome (mo)
HELPS¹	HydroCoil^b versus bare platinum coil	Composite	Yes	Major/minor Raymond	NA	No	18
MAPS⁵	Matrix Coil^c versus bare platinum coil	Composite	No	NA	NA	Yes	12
CCT^2–4	Cerecyte Coil versus bare platinum coil	Simple	No	NA	Angiographic occlusion, improvement, or no change	No	6
Efficacy Trial of Intracranial Aneurysm Treatment Using 2 Different Endovascular Techniques	Coils versus Silk^d artery reconstruction device	Simple	No	NA	NA	No	12
Hydrogel Coil Versus Bare Platinum Coil in Recanalization Imaging Data Study	HydroCoil versus bare platinum coil	Simple	Yes	NA	NA	No	12
Flow Diversion in Intracranial Aneurysm Treatment	Flow diversion versus best standard treatment	Composite	No	NA	NA	No	12
The Canadian Unruptured Endovascular Versus Surgery Trial	Endovascular coiling versus surgical clipping	Composite	Yes	NA	NA	No	12
HydroCoil Cerebral Aneurysm Treatment Trial	HydroCoil versus bare platinum coil	Simple	Yes	NA	Angiographic occlusion, improvement, or no change	No	12–18
Hydrogel Endovascular Aneurysm Treatment Trial	HydroCoil versus bare platinum coil	Simple	Yes	Raymond scale or Meyers Scale	NA	No	24
Patients Prone to Recurrence After Endovascular Treatment	HydroCoil versus bare platinum coil	Simple	Yes	NA	NA	No	18

Note:—NA indicates not applicable.
↵a Data were obtained from www.clinicaltrials.gov using search terms “aneurysm” and “intracranial aneurysm.”
↵b MicroVention Terumo, Aliso Viejo, California.
↵c Boston Scientific, Natick, Massachusetts.
↵d Balt, Montmorency, France.