Review of Cases of Cerebral Amyloidomas
| Author and Year* | Patient (no.)/ Age (y)/Sex | Clinical Presentation | Location | No. of Lesions | CT Findings | MR Imaging Findings | Angiographic Findings |
|---|---|---|---|---|---|---|---|
| Saltykow, 1935 (5) | 1/Unknown | Psychiatric disturbances | Cortex, WM | M | NA | NA | NA |
| Harris and Rayport, 1979 (6) | 2/28/F | Focal seizures | Frontal WM | S | Hyperattenuating mass on nonenhanced scans | NA | NA |
| Spaar et al, 1981 (7) | 3/46/F | Visual loss, headache, depression | WM | M | Hypoattenuating lesions, enhancement on contrast-enhanced scans, extension to the lateral ventricle | NA | Vascular displacements |
| Townsend et al, 1982 (8) | 4/47/F | Cognitive decline | Frontal/optic radiation, WM | M | Hyperattenuating mass on nonenhanced scans | NA | Absent venous filling in the affected region |
| Townsend et al, 1982 (8) | 5/50/M | Visual field defects | Occipital WM | S | Hyperattenuating mass with enhancement on contrast-enhanced scans | NA | NA |
| Moreno et al, 1983 (9) | 6/48/M | R hemianopsia, L-arm weakness | L occipital WM | S | Ring-enhancing lesion, extension to the lateral ventricle, thickened ependyma | NA | Normal |
| Hori et al, 1988 (10) | 7/60/M | Headache, seizure, dementia | L frontal, cerebellum, pons (WM) | M | NA | NA | NA |
| Cohen et al, 1992 (11) | 8/32/M | Headache, seizure, decreased cognition | Bilateral centrum semiovale WM, 1 cortical lesion | M | Hyperattenuating masses, contrast enhancement, extension to the lateral ventricle | Hypointense on T1WI, mixed intensity on T2WI, faint enhancement | NA |
| Eriksson et al, 1993 (2) | 9/76/M | Seizure | R parietal WM, extension to lateral ventricle and choroid plexus | S | NA | NA | Mass effect on the temporal horn of the lateral ventricle |
| Schroder et al, 1995 (12) | 10/70/F | Ataxia, L-leg weakness, cognitive decline | R subcortical parieto-occipital, 2 smaller lesions in the ventricular wall | M | Hyperattenuating, no edema, extension to the lateral ventricle | NA | Normal |
| Lee et al, 1995 (3) | 11/61/F | Seizures, decreased mentation | L parietal periatrial WM | S | Hyperattenuating, partially calcified, no edema | Hyperintense on T1WI, mixed intensity on T2WI, marked enhancement, no edema, extension to the lateral ventricle | NA |
| Caerts et al, 1997 (4) | 12/71/F | R pyramidal syndrome | L deep periventricular WM | S | Hyperattenuating mass on nonenhanced scans, contrast enhancement, no edema | Isointense on T1WI, hyperintense on T2WI, strongly enhancing, extension to the lateral ventricle | NA |
| Blatter et al, 2001 (22) | 13/26/F | R-hand paresis, dysarthria | L parieto-occipital, smaller R-sided lesions | M | NA | T1WI and T2WI appearance unknown, contrast enhancement, extension to the lateral ventricle | NA |
| Gandhi et al, 2003 (present case) | 14/54/F | Seizures | L frontal WM, medial extension to the lateral ventricle | S | Comet-shaped hyperattenuating mass on nonenhanced scans, contrast enhancement, medial extension up to lateral ventricle wall | Hypointense on T1WI and T2WI, strong contrast enhancement, surrounding edema | NA |
Note.—L indicates left; M, multiple; NA, not applicable; R, right; S, single; T1WI, T1-weighted image; T2WI, T2-weighted image; and WM, white matter.
* Numbers in parentheses are reference numbers.