TABLE 1:

Clinical, laboratory, and MR imaging findings in patients with ADEM at presentation

Patient No./Age(y)/SexMain Clinical FeaturesClinical OutcomeMR Imaging Findings at PresentationMR Imaging Findings at ≥6 MoCSF Findings
1/47/MConfusion, left hemiparesisComplete recoveryMultiple brain WM lesionsComplete resolution of lesionsNot obtained
2/22/MTetraparesis, urine retentionComplete recoveryMultiple brain and spinal cord WM lesions, one hyperintense lesion in the left thalamusMarked but incomplete resolution of brain lesions, complete resolution of cord lesionsCells increased, OB
3/21/FDrowsiness, right hemiparesisComplete recoveryMultiple brain WM lesions, one hyperintense lesion in the left basal gangliaIncomplete resolution of lesionsCells and protein level increased
4/37/FConfusion, left hemiparesisAlmost complete recoveryMultiple brain WM lesionsIncomplete resolution of lesionsCells increased
5/31/FDrowsiness, right hemiparesisComplete recoveryMultiple brain WM lesionsComplete resolution of lesionsNormal
6/40/FParaparesis, urine retentionComplete recoveryMultiple brain and spinal cord WM lesionsMarked but incomplete resolution of brain and cord lesionsCells and protein level increase, OB
7/22/MDrowsiness, diplopia, tetraparesis, ataxiaComplete recoveryMultiple brain WM lesionsIncomplete resolution of lesionsProtein level increased
8/51/MAtaxia, paraparesisMarked improvementMultiple brain and spinal cord WM lesionsIncomplete resolution of brain and cord lesionsProtein level increased, OB

  • Note.—OB indicates oligoclonal bands; WM, white matter.