Comparison of clinical/CTA characteristics between patients with and without improvement of aphasia (univariate analysis)
| Aphasia Improvement (n = 21) | No Improvement (n = 37) | P Value | |
|---|---|---|---|
| Age | 69.5 ± 3.8 | 76.8 ± 1.9 | .10 |
| Female | 11 (52%) | 21 (57%) | .78 |
| Admission NIHSS score | 8 (2–23) | 19 (5–28) | .001a |
| Admission aphasia NIHSS score | 2 (1–3) | 3 (1–3) | .002a |
| Major proximal arterial occlusion | 7 (33%) | 30 (81%) | .001a |
| Thrombolytic therapy (IV) | 5 (24%) | 11 (29%) | .76 |
| IA thrombectomyb | 1 (5%) | 3 (8%) | 1.00 |
| Ictus to IV treatment interval (hour) | 2.11 ± 0.25 | 1.93 ± 0.25 | .67 |
| IV treatment to CTP interval (hour)c | 1.13 ± 0.49 | 1.51 ± 0.52 | .68 |
| Ictus to CTP interval (hour) | 4.46 ± 0.57 | 4.78 ± 0.48 | .68 |
a Significant.
b Of the 4 patients who received thrombectomy, only 1, who had complete recanalization, subsequently showed language improvement. All patients who received thrombectomy had first received IV thrombolysis.
c Only 1 patient with and 4 without language improvement received IV thrombolysis following CTP; negative treatment-to-CTP-time values were calculated for these patients.