Table 3:

ROC curve analysis of PCT parameters for early response (tumor volume shrinkage ≥30%) to concomitant chemoradiotherapy

Value	Criterion	AUC	P	Sensitivity, %	Specificity, %	Positive LR	Negative LR
Baseline BF	>70.4	0.54	.4	57.3	80.0	3.0	0.6
BF (40 Gy)	≤*74.4*	*0.82*	*.03*	*90.0*	*80.0*	*4.4*	*0.2*
Baseline BV	≥*5.0*	*0.83*	*.01*	*59.5*	*100*		*0.4*
BV (40 Gy)	≤*6.9*	*0.80*	*.02*	90	80	*5.2*	*0.0*
Baseline MTT	≤9.0	0.60	.8	71.4	60	1.8	0.5
MTT (40 Gy)	≤*9.2*	*0.83*	*.04*	*100*	60	*2.4*	*0.0*
Baseline PS	>10.0	0.63	.1	100	60	2.2	0.0
PS (40 Gy)	≤12.6	0.80	.06	65	100		0.4

Note:—The values of the provided criteria are the cutoff thresholds for predicting the defined early response. The statistically significant values (P ≤.05) are set in boldface italics; the values approaching statistical significance (P = .06) are set in lightface italics. Values for BF are in mL/min/100 g; for BV, mL/100 mL; for MTT, seconds; and for PS, mL/min/100 g.