Patient characteristics by time to IV tPA initiation
| Characteristic | ≤60 Minutes to tPA (n = 67) | >60 Minutes to tPA (n = 56) | P Value |
|---|---|---|---|
| Multimodal CT imaging | 92.5 (62) | 82.1 (46) | .08 |
| Age ≥65 | 68.7 (46) | 66.1 (37) | .76 |
| Female sex | 59.7 (40) | 58.9 (33) | .93 |
| Prehospital stroke notification | 89.6 (60) | 73.2 (41) | .02a |
| Peak arrival time (12pm to 12 am) | 43.3 (29) | 35.7 (20) | .39 |
| Weekday arrival (Monday–Friday) | 67.2 (45) | 73.2 (41) | .47 |
| Initial NIHSS score ≥ 8 | 68.2 (45) | 53.7 (29) | .10 |
| Onset-to-arrival timea | 50 (35–83) | 44 (35–63) | .10 |
| Arrival to CT start timea | 10 (6–15) | 14 (9–26) | .01 |
| Door-to-needle timeb | 43 (37–50) | 83.5 (70–95) | <.001 |
| Yearb | .25 | ||
| 2006 | 34.3 (23) | 28.6 (16) | |
| 2007 | 34.3 (23) | 28.6 (16) | |
| 2008 | 31.4 (21) | 42.9 (24) |
a Event times are shown as median (IQR).
b Cochran-Armitage test for trend.