Table 5:

VBM results of the comparison between MCI converters and MCI nonconverters adjusting for gender, age, global gray matter volume, and delayed NYU paragraph recall*

MNI MaxpClusterKTpFDRCluster %R/LLocation
−34 -57 510.07931 (0.9 cm3)50.0670.03LeftAngular gyrus
29.22LeftInferior parietal lobule
−54 -42 100.06941 (0.9 cm3)4.40.0681.08LeftSuperior temporal gyrus
18.92LeftMiddle temporal gyrus
  • Note:—pCluster indicates p cluster corrected; K, cluster size; T, T value; pFDR, p false discovery rate; VBM, voxel-based morphometry; MCI, mild cognitive impairment; MNI, Montreal Neurologic Institute.

  • * Statistics calculated within a brain mask comprising only temporal and parietal lobes. Thresholding was performed at P < .0001 (uncorrected), and subsequently only the cluster surviving corrected thresholds reported pCluster = .1, pFDR voxel-level corrected = .1, cluster extent = 70 = 0.7 cm3.