VBM results of the comparison between MCI converters and MCI nonconverters adjusting for gender, age, global gray matter volume, and delayed NYU paragraph recall*
| MNI Max | pCluster | K | T | pFDR | Cluster % | R/L | Location |
|---|---|---|---|---|---|---|---|
| −34 -57 51 | 0.07 | 931 (0.9 cm3) | 5 | 0.06 | 70.03 | Left | Angular gyrus |
| 29.22 | Left | Inferior parietal lobule | |||||
| −54 -42 10 | 0.06 | 941 (0.9 cm3) | 4.4 | 0.06 | 81.08 | Left | Superior temporal gyrus |
| 18.92 | Left | Middle temporal gyrus |
Note:—pCluster indicates p cluster corrected; K, cluster size; T, T value; pFDR, p false discovery rate; VBM, voxel-based morphometry; MCI, mild cognitive impairment; MNI, Montreal Neurologic Institute.
* Statistics calculated within a brain mask comprising only temporal and parietal lobes. Thresholding was performed at P < .0001 (uncorrected), and subsequently only the cluster surviving corrected thresholds reported pCluster = .1, pFDR voxel-level corrected = .1, cluster extent = 70 = 0.7 cm3.