Table 3:

Relationship between FA (%) and WMSA*

Brain RegionWMSA on MRIP Values
Normal (n = 39)Focal (n = 59)Extensive (n = 13)OverallNormal vs FocalNormal vs ExtensiveFocal vs Extensive
Inferior frontal
    Right15.1 (4.62)13.35 (4.87)9.14 (6.80).002.29.001.02
    Left16.71 (4.53)14.10 (4.96)13.82 (6.73).15.33.10.99
Inferior occipital
    Right18.15 (4.78)16.35 (4.32)15.56 (4.53).09.17.23.99
    Left18.53 (5.41)17.34 (5.65)15.42 (2.78).18.84.21.73
Internal capsule
    Right51.01 (4.39)50.46 (4.08)43.95 (7.62)<.001.99<.001<.001
    Left48.85 (5.62)48.36 (4.32)43.51 (7.69).006.99.006.01
Superior frontal
    Right14.24 (3.89)12.71 (3.34)13.02 (5.43).15.16.96.99
    Left15.82 (4.34)13.93 (4.19)13.68 (4.78).08.11.37.99
Sensorimotor
    Right21.50 (7.78)19.74 (7.50)16.65 (5.00)).12.75.13.52
    Left20.82 (7.22)19.64 (6.52)18.10 (4.07.40.99.60.99
Superior occipital
    Right16.69 (5.45)16.51 (3.99)12.22 (5.60).01.99.01.01
    Left16.16 (4.31)15.92 (4.04)13.73 (5.31).20.99.24.30
  • Note:—FA indicates fractional anisotropy.

  • * Values are mean (SD).

  • P values after Bonferroni correction.

  • Significant P values.