Experimental data
| Swine No. | Side | Solvent Infused (0.8 mL/60 s) | % of Vessel Narrowing/Vasospasm Score After: | |||||
|---|---|---|---|---|---|---|---|---|
| 3 min | 8 min | 13 min | 18 min | 23 min | 28 min | |||
| 1 | Right | DMSO | 50/2.5 | 51/2.5 | 41/2 | 36/2 | 23/2 | 15/1 |
| Left | Glycofurol 75 | 65/3 | 45/2 | 0/0 | 0/0 | |||
| 2 | Right | DMI | 0/0 | 0/0 | 0/0 | |||
| Left | NMP | 28/2 | 18/1 | 0/0 | ||||
| 3 | Right | Solketal | 50/2.5 | 20/1 | 0/0 | 0/0 | ||
| Left | Ethyl lactate | 50/2.5 | 19/1 | 0/0 | 0/0 | |||
| 4 | Right | DMSO | 82/4 | 35/2 | 0/0 | 0/0 | ||
| Left | DMI | 32/2 | 21/1 | 0/0 | ||||
| 5 | Right | NMP | 0/0 | 0/0 | 0/0 | |||
| Left | Solketal | 41/2 | 0/0 | 0/0 | ||||
| 6 | Right | Glycofurol 75 | 45/2 | 23/1 | 18/1 | 0/0 | ||
| Left | Ethyl lactate | 82/4 | 23/1 | 0/0 | 0/0 | |||
| 7 | Right | DMSO | 36/2 | 21/1 | 17/1 | 0/0 | 0/0 | |
| Left | NMP | 14/1 | 0/0 | 0/0 | ||||
| 8 | Right | Glycofurol 75 | 21/1 | 0/0 | 0/0 | |||
| Left | DMI | 23/1 | 15/1 | 0/0 | ||||
| 9 | Right | Ethyl lactate | 40/2 | 20/1 | 0/0 | 0/0 | ||
| Left | NMP | 0/0 | 0/0 | 0/0 | ||||
| 10 | Right | DMSO | 68/3 | 40/2 | 18/1 | 11/1 | 0/0 | 0/0 |
| Left | Solketal | 53/3 | 50/2.5 | 13/1 | 0/0 | |||
| 11 | Right | DMI | 39/0 | 0/0 | 0/0 | |||
| Left | Ethyl lactate | 42/2 | 26/1.5 | 14/1 | 0/0 | |||
| 12 | Right | Glycofurol 75 | 36/2 | 16/1 | 0/0 | 0/0 | ||
| Left | Solketal | 59/3 | 25/1.5 | 0/0 | 0/0 | |||
| 13 | Right | NMP | 17/1 | 0/0 | 0/0 | |||
| Left | DMI | 0/0 | 0/0 | 0/0 | ||||
| 14 | Right | NMP | 10/1 | 0/0 | 0/0 | |||
| Left | Glycofurol 75 | 38/2 | 18/1 | 0/0 | 0/0 | |||
Note:—DMSO indicates dimethyl sulfoxide; DMI, dimethyl isosorbide; NMP, N-methyl-2-pyrollidone.