Detection of metabolites normally not found in the human brain
Glc 3.44 ppm* | Lac* | Lip* | Other Metabolites* | |
---|---|---|---|---|
Glioblastomas (pt no.) | ||||
1 | ++ | + | Val, Leu, Ile | |
2 | + | + | Val, Leu, Ile | |
3 | + | ++ | + | Val, Leu, Ile, Ala |
4 | + | + | Val, Leu, Ile | |
5 | ++ | + | ||
6 | + | + | + | Val, Leu, Ile |
7 | + | Val, Leu, Ile | ||
Metastases (pt no.) | ||||
8 | ++ | + | Val, Leu, Ile | |
9 | + | + | Val, Leu, Ile | |
10 | + | + | Val, Leu, Ile | |
Meningiomas (pt no.) | ||||
11 | + | ++ | + | Val, Leu, Ile |
12 | +++ | ++ | Val, Leu, Ile | |
13 | ++ | + | + | Val, Leu, Ile, Ala |
Note:—Glc indicates glucose; Lac, lactate; Lip, lipids; Val, valine; Leu, leucine; Ile, isoleucine; and Ala, alanine.
* Peak resonances of Glc, Lac, and Lip detected and arbitrarily assigned to 1 of 3 grades, low (+), medium (++), or high (+++) on the basis of the ratio of the integral of the metabolite peak to the integral of unsuppressed water peak. For Val, Leu, Ile, and Ala, only their presence is indicated.