Table 2:

Brain volume (milliliters) differences between values at week 0 and week 12, expressed in several ways*

Structure	Absolute Difference		Max Volume Change		Max Percent Change
Structure	Mean	SD	Decrease	Increase	Decrease	Increase
Whole brain	17.9	17.7	−68.3	77.3	−5.7	6.5
L frontal GM	3.3	3.6	−6.7	19.8	−4.3	12.6
R frontal GM	3.0	2.9	−6.3	17.8	−3.9	11.1
L occipital GM	1.6	1.4	−5.2	7.4	−8.8	12.5
R occipital GM	1.4	1.6	−5.1	6.8	−8.6	11.4
L parietal GM	1.6	1.2	−5.9	4.8	−9.4	7.7
R parietal GM	1.7	1.8	−7.1	8.5	−11.1	13.3
L temporal GM	2.2	2.1	−6.0	9.4	−8.9	13.9
R temporal GM	2.4	2.3	−7.7	10.7	−11.2	15.6
L frontal WM	3.8	3.7	−9.7	21.3	−6.8	15.0
R frontal WM	3.9	3.6	−11.1	21.1	−7.8	14.8
L occipital WM	1.0	1.0	−3.4	3.6	−19.9	21.1
R occipital WM	1.0	0.8	−2.9	3.2	−16.6	18.3
L parietal WM	1.3	1.2	−7.1	3.6	−15.4	7.8
R parietal WM	1.5	1.1	−5.1	3.5	−11.1	7.6
L temporal WM	1.5	1.5	−6.5	5.7	−18.1	15.8
R temporal WM	1.6	1.4	−5.0	6.5	−13.9	18.0
L caudate	0.4	0.3	−1.2	2.1	−27.9	48.8
R caudate	0.4	0.4	−2.1	1.8	−43.8	37.5

Note:—L, left; R, right; Max, maximum; GM, gray matter; WM, white matter.
* The absolute difference is unaffected by the sign of the change from week 0 to week 12. The maximal decrease and increase from week 0 to week 12 is expressed as volume (with units of milliliters) and as percent change (with respect to baseline).