Whole-brain volumetric measures in ALS patients and healthy subjects
| Healthy Subjects | ALS Patients | P | |
|---|---|---|---|
| BPF | 0.849 (0.019) | 0.827 (0.019) | 0.012 |
| NBV [ml] | 1433.9 (86.1) | 1392.4 (78.9) | NS |
| NGMV [ml] | 724.6 (43.6) | 711.5 (46.6) | NS |
| NWMV [ml] | 709.3 (48.5) | 680.9 (46.4) | NS |
Note:—P values were determined with the use of the Mann Whitney U test. BPF indicates brain parenchymal fraction; NBV, normalized brain volume; NGMV, normalized gray matter volume; NWMV, normalized white matter volume.